Tvedt B, Skyberg K, Aaserud O, Hobbesland A, Mathiesen T
National Institute of Occupational Health, Oslo, Norway.
Am J Ind Med. 1991;20(1):91-101. doi: 10.1002/ajim.4700200109.
Hydrogen sulfide (H2S) poisoning involves a risk of hypoxic brain damage. Six patients who lost consciousness due to H2S poisoning are described. The symptoms varied from anosmia in the patient with the shortest but highest exposure to delayed neurological deterioration in the patient with the longest exposure. The two patients with the most serious symptoms developed pulmonary edema, which may have prolonged the hypoxia. The patients were reexaminated 5 years or more after the poisoning. The five patients who had been unconscious in H2S atmosphere for from 5 to 15-20 min showed persisting impairment at neurological and neuropsychological re-examination. Memory and motor function were most affected. One patient was seriously demented. Recent reports of large groups of H2S-poisoned workers probably underestimate the risk of sequelae, due to the inclusion of cases with exposure of short duration and lack of follow-up.
硫化氢（H₂S）中毒存在导致缺氧性脑损伤的风险。本文描述了6例因硫化氢中毒而失去意识的患者。症状表现各异，从接触时间最短但浓度最高的患者出现嗅觉丧失，到接触时间最长的患者出现迟发性神经功能恶化。两名症状最严重的患者发生了肺水肿，这可能延长了缺氧时间。这些患者在中毒5年或更长时间后接受了复查。在硫化氢环境中失去意识5至15 - 20分钟的5名患者在神经学和神经心理学复查中显示出持续的损伤。记忆和运动功能受影响最大。一名患者出现严重痴呆。近期关于大量硫化氢中毒工人的报告可能低估了后遗症的风险，因为纳入了接触时间短的病例且缺乏随访。
