Pereira A, Monteagudo J, Rovira M, Mazzara R, Reverter J C, Castillo R
Department of Hemotherapy and Hemostasis, Hospital Clínico, University of Barcelona, Spain.
Transfusion. 1989 Jul-Aug;29(6):549-51. doi: 10.1046/j.1537-2995.1989.29689318457.x.
An anti-K1 alloantibody developed in a patient infected with Morganella morganii. The serologic behavior and response to dithiothreitol initially suggested that the alloantibody was an IgM. However, flow cytometry and the separation of immunoglobulin classes by serum chromatography revealed that the anti-K1 was constituted solely of IgA. These data suggest that bacteria-induced red cell antibodies might be of the IgA class.
一名感染摩根氏摩根菌的患者体内产生了一种抗K1同种抗体。血清学行为及对二硫苏糖醇的反应最初表明该同种抗体是IgM。然而,流式细胞术及血清色谱法对免疫球蛋白类别的分离显示,抗K1仅由IgA构成。这些数据表明,细菌诱导产生的红细胞抗体可能属于IgA类别。