Roothans Dessie, van Ierssel Sabrina, Moorkens Greta
a Department of General Internal Medicine , Antwerp University Hospital , Belgium.
Acta Clin Belg. 2017 Aug;72(4):264-267. doi: 10.1080/17843286.2016.1218177. Epub 2016 Aug 6.
Q fever is a zoonosis caused by the intracellular bacterium Coxiella burnetii. While it is mostly an asymptomatic infection, acute disease can manifest as fever associated with signs of pneumonia or hepatitis. Chronic Q fever develops in 1-5% of infected persons. Patients with a history of cardiac valve surgery, vascular prosthesis or vascular aneurysm, and to a lesser extent patients with pre-existing valvular disease, immune deficiencies, or renal insufficiency, are at highest risk. Most common manifestations are Q fever endocarditis and Q fever vascular infection. We present a case of chronic Q fever, followed by a summary of available literature.
Q热是一种由细胞内细菌伯纳特立克次体引起的人畜共患病。虽然它大多为无症状感染,但急性疾病可表现为发热并伴有肺炎或肝炎迹象。1%至5%的感染者会发展为慢性Q热。有心脏瓣膜手术史、血管假体或血管动脉瘤病史的患者,以及在较小程度上有既往瓣膜疾病、免疫缺陷或肾功能不全的患者,风险最高。最常见的表现是Q热心内膜炎和Q热血管感染。我们报告一例慢性Q热病例,随后对现有文献进行总结。