Moreno Jonathan D
Perspect Biol Med. 2016;59(1):107-21. doi: 10.1353/pbm.2016.0019.
Henry Knowles Beecher, an icon of human research ethics, and Timothy Francis Leary, a guru of the counterculture, are bound together in history by the synthetic hallucinogen lysergic acid diethylamide (LSD). Both were associated with Harvard University during a critical period in their careers and of drastic social change. To all appearances the first was a paragon of the establishment and a constructive if complex hero, the second a rebel and a criminal, a rogue and a scoundrel. Although there is no evidence they ever met, Beecher's indirect struggle with Leary over control of the 20th century's most celebrated psychedelic was at the very heart of his views about the legitimate, responsible investigator. That struggle also proves to be a revealing bellwether of the increasingly formalized scrutiny of human experiments that was then taking shape.
亨利·诺尔斯·比彻,人类研究伦理的标志性人物,以及蒂莫西·弗朗西斯·利里,反主流文化的宗师,在历史上因合成致幻剂麦角酸二乙酰胺(LSD)而联系在一起。在他们职业生涯的关键时期以及社会剧烈变革期间,两人都与哈佛大学有关联。表面上看,前者是体制的典范,是一位有建设性但复杂的英雄,后者是叛逆者和罪犯,是无赖和恶棍。尽管没有证据表明他们曾见过面,但比彻与利里围绕20世纪最著名的迷幻药控制权展开的间接斗争,正是他关于合法、负责的研究者观点的核心所在。那场斗争也被证明是当时正在形成的对人体实验日益正规化审查的一个具有启发性的预兆。