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亨利·K·比彻与儿童研究的监督

Henry K. Beecher and the Oversight of Research in Children.

作者信息

Lantos John

出版信息

Perspect Biol Med. 2016;59(1):95-106. doi: 10.1353/pbm.2016.0017.

DOI:10.1353/pbm.2016.0017
PMID:27499487
Abstract

Henry K. Beecher was a pioneer of research ethics and a prominent whistleblower with regard to ethically problematic studies. Most of his work focused on research in adults, not children, but he did speculate about the implications of his ethical concerns for research in minors. This paper reviews Beecher's response to Krugman's studies of hepatitis at the Willowbrook State School and the debate that Beecher's article stimulated between Ramsey and McCormick. That debate shaped the terms that were used in current federal regulations for research in children. The paper then speculates about whether Beecher would have approved of our current regulatory system.

摘要

亨利·K·比彻是研究伦理的先驱,也是涉及伦理问题研究的杰出举报人。他的大部分工作集中于成人研究,而非儿童研究,但他确实推测了其伦理关切对未成年人研究的影响。本文回顾了比彻对克鲁格曼在柳树溪州立学校进行的肝炎研究的回应,以及比彻的文章引发的拉姆齐和麦考密克之间的辩论。那场辩论塑造了当前联邦儿童研究法规所使用的术语。本文接着推测比彻是否会认可我们当前的监管体系。

相似文献

1
Henry K. Beecher and the Oversight of Research in Children.亨利·K·比彻与儿童研究的监督
Perspect Biol Med. 2016;59(1):95-106. doi: 10.1353/pbm.2016.0017.
2
Henry Beecher and Consent to Research: a critical re-examination.亨利·比彻与研究同意书:一次批判性的重新审视
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Henry Beecher's Contributions to the Ethics of Clinical Research.亨利·比彻对临床研究伦理的贡献。
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The Role of the Virtuous Investigator in Protecting Human Research Subjects.道德研究者在保护人类研究受试者方面的作用。
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"The Warmth of His Continuing Interest": Henry K. Beecher, the Bioethics Revolution, and Pharmaceutical Industry Funding of Academic Medical Science in Cold War America.
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Clinical Trials Without Consent?未经同意的临床试验?
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The ethical challenges of animal research.动物研究的伦理挑战。
Camb Q Healthc Ethics. 2015 Oct;24(4):391-406. doi: 10.1017/S0963180115000067.
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Beecher Reconsidered.重新审视比彻尔。
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