Lantos John
Perspect Biol Med. 2016;59(1):95-106. doi: 10.1353/pbm.2016.0017.
Henry K. Beecher was a pioneer of research ethics and a prominent whistleblower with regard to ethically problematic studies. Most of his work focused on research in adults, not children, but he did speculate about the implications of his ethical concerns for research in minors. This paper reviews Beecher's response to Krugman's studies of hepatitis at the Willowbrook State School and the debate that Beecher's article stimulated between Ramsey and McCormick. That debate shaped the terms that were used in current federal regulations for research in children. The paper then speculates about whether Beecher would have approved of our current regulatory system.
亨利·K·比彻是研究伦理的先驱,也是涉及伦理问题研究的杰出举报人。他的大部分工作集中于成人研究,而非儿童研究,但他确实推测了其伦理关切对未成年人研究的影响。本文回顾了比彻对克鲁格曼在柳树溪州立学校进行的肝炎研究的回应,以及比彻的文章引发的拉姆齐和麦考密克之间的辩论。那场辩论塑造了当前联邦儿童研究法规所使用的术语。本文接着推测比彻是否会认可我们当前的监管体系。