Sadeh-Mestechkin Dana, Samara Nivin, Wiser Amir, Markovitch Ofer, Shechter-Maor Gil, Biron-Shental Tal
Department of Obstetrics and Gynecology, Meir Medical Center, 59 Tschernichovsky, 44282, Kfar Saba, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Arch Gynecol Obstet. 2016 Nov;294(6):1203-1207. doi: 10.1007/s00404-016-4165-z. Epub 2016 Aug 8.
To compare maternal and neonatal outcomes in induced vs. expectant management of term PROM.
This retrospective study included patients with term PROM. A total of 325 were enrolled: 213 managed expectantly and 112 induced at admission and matched according to gestational age. Expectant management group patients were allowed to defer labour induction up to 48 h. Primary outcome measures were maternal or foetal signs of infection (chorioamnionitis, early neonatal sepsis or postpartum endometritis) and prolonged maternal hospitalization. Secondary outcome was caesarean delivery rate.
All group characteristics were comparable except that expectant management included more nulliparous women. Women managed expectantly had a higher rate of prolonged hospitalization [15 (7 %) vs. 2 (1.8 %); P = 0.043] as an indication of maternal complications, compared to induction management. They also had a higher rate of caesarean delivery [34 (16.4 %) vs. 8 (7.1 %), respectively; P = 0.024]. Adjustment for parity did not change the results. Early neonatal outcomes were similar between groups.
Expectant management increases the likelihood of caesarean delivery and prolonged maternal hospitalization. This should be considered when advising patients with term PROM regarding labour induction.
比较足月胎膜早破引产与期待治疗的母婴结局。
这项回顾性研究纳入了足月胎膜早破患者。共纳入325例:213例接受期待治疗,112例入院时引产,并根据孕周进行匹配。期待治疗组患者可将引产推迟至48小时。主要结局指标为母体或胎儿感染迹象(绒毛膜羊膜炎、早发型新生儿败血症或产后子宫内膜炎)及产妇住院时间延长。次要结局为剖宫产率。
除期待治疗组初产妇更多外,所有组特征均具有可比性。与引产治疗相比,期待治疗的产妇因母体并发症导致住院时间延长的发生率更高[15例(7%)对2例(1.8%);P = 0.043]。她们的剖宫产率也更高[分别为34例(16.4%)对8例(7.1%);P = 0.024]。对产次进行调整后结果未改变。两组间早期新生儿结局相似。
期待治疗增加了剖宫产及产妇住院时间延长的可能性。在为足月胎膜早破患者提供引产建议时应考虑到这一点。