Akın Onur, Eker İbrahim, Arslan Mutluay, Taşdemir Serdar, Taşçılar Mehmet Emre, Ulaş Ümit Hıdır, Yeşilkaya Ediz, Ünay Bülent
Department of Pediatric Endocrinology, Gülhane Military Medical Academy, Ankara, Turkey.
Department of Pediatrics, Gülhane Military Medical Academy, Ankara, Turkey.
Childs Nerv Syst. 2016 Nov;32(11):2219-2224. doi: 10.1007/s00381-016-3210-3. Epub 2016 Aug 9.
The objective of our study was to investigate nerve conduction in normoglycemic obese children.
A total of 60 children with obesity (30 female and 30 male) and 30 healthy children (15 female and 15 male) were enrolled in the study. Insulin resistance (IR) and other metabolic disturbances were investigated and nerve conduction was measured in all participants. Obese children were divided into groups according to the presence of IR. All results were compared between these subgroups.
The nerve conduction velocity (NCV) of motor median nerves in the IR+ group was significantly higher than that in the IR- group and lower than that in the control group. The NCV of the motor peroneal nerve in the IR+ group was significantly lower than that in the IR- group. The sensory nerve action potential (SNAP) of the sensory median nerve was significantly lower in the IR+ group compared to that in the IR- group. The sensory sural nerve's SNAP was significantly lower in the IR+ group than that in the control group.
Nerve conduction tests may help to detect early pathologies in peripheral nerves and to decrease morbidities in obese children.
本研究的目的是调查血糖正常的肥胖儿童的神经传导情况。
共有60名肥胖儿童（30名女性和30名男性）和30名健康儿童（15名女性和15名男性）参与了本研究。对所有参与者进行胰岛素抵抗（IR）和其他代谢紊乱情况的调查，并测量神经传导。肥胖儿童根据是否存在IR进行分组。对这些亚组之间的所有结果进行比较。
IR+组运动正中神经的神经传导速度（NCV）显著高于IR-组且低于对照组。IR+组运动腓总神经的NCV显著低于IR-组。IR+组感觉正中神经的感觉神经动作电位（SNAP）显著低于IR-组。IR+组腓肠感觉神经的SNAP显著低于对照组。
神经传导测试可能有助于检测肥胖儿童外周神经的早期病变并降低发病率。
