Gebreegziabher Daniel, Asfeha Gebrekidan Gebregzabher, Gebreyesus Hagos Amare
Medical Laboratory Technology, Institute of Biomedical Sciences, Mekelle University, Mekelle, Ethiopia.
Medical biochemistry, Institute of Biomedical Sciences, Mekelle University, Mekelle, Ethiopia.
BMC Infect Dis. 2016 Aug 8;16:383. doi: 10.1186/s12879-016-1744-3.
Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people.
The aim of this study was to determine the prevalence of hepatitis B virus in Tefera Hailu Memorial Hospital (THMH) for the last three years (2013, 2014, 2015) by using secondary data.
A three year retrospective record review was conducted from March 01/2015-July 30/2015. All registered data for hepatitis B virus serological screening of the specified period were included. The data were collected by predesigned data collection sheet. The sample size was calculated by simple statistical estimation to be 149 for each year.
Of 482 subjects, 215 (44.60 %) were females and 267 (55.40 %) were males. The overall prevalence of HBV was 102 (21.16 %). The positivity rate was 69 (14.31 %) in the age group between 15 and 45. There was a decrease in the prevalence of HBV from 2012 up to 2014.
The seroprevalence of HBsAg was higher in males than in females and the yearly prevalence decreases from 2012-2014. But HBV infection is still a public health problem in Ethiopia. Therefore intensification of health education concerning modes of transmission and prevention of HBV, early case finding and treatment is recommended to reduce the spread of the disease.
乙型肝炎病毒是人类肝脏疾病的主要致病因子之一,包括急性和慢性肝炎、肝硬化及肝细胞癌。该疾病是全球重大的健康问题,估计有3.5亿慢性感染者。
本研究旨在通过使用二手数据确定特费拉·海卢纪念医院(THMH)过去三年(2013年、2014年、2015年)乙型肝炎病毒的流行情况。
于2015年3月1日至2015年7月30日进行了为期三年的回顾性记录审查。纳入了特定时期内所有乙型肝炎病毒血清学筛查的登记数据。数据通过预先设计的数据收集表收集。每年的样本量通过简单统计估计为149例。
在482名受试者中,女性215名(44.60%),男性267名(55.40%)。HBV的总体流行率为102例(21.16%)。15至45岁年龄组的阳性率为69例(14.31%)。从2012年到2014年,HBV的流行率有所下降。
男性HBsAg的血清流行率高于女性,且从2012年到2014年逐年下降。但HBV感染在埃塞俄比亚仍是一个公共卫生问题。因此,建议加强关于HBV传播方式和预防、早期病例发现及治疗的健康教育,以减少疾病传播。