Weekes Anthony J, Oh Laura, Thacker Gregory, Johnson Angela K, Runyon Michael, Rose Geoffrey, Johnson Thomas, Templin Megan, Norton H James
Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina USA
Emory University, Atlanta, Georgia USA.
J Ultrasound Med. 2016 Oct;35(10):2113-20. doi: 10.7863/ultra.15.11007. Epub 2016 Aug 8.
To evaluate observer agreement using qualitative goal-directed echocardiographic criteria for right ventricular (RV) dysfunction prognostication in submassive pulmonary embolism (PE).
Two emergency physicians and 2 cardiologists independently reviewed 31 packets of goal-directed echocardiographic video clips consisting of at least 3 windows obtained by emergency physicians from normotensive patients with PE. Nine packets were repeated to assess for intraobserver agreement. Right ventricular dysfunction criteria on goal-directed echocardiography were as follows: RV enlargement was present, with a right-to-left ventricular basal diameter ratio of 1.0 or higher and blunting of the apex of the RV in 2 or more different windows; RV systolic dysfunction was present if the tricuspid annulus moved toward the apex 10 mm or less and there was RV free wall hypokinesis; and septal deviation was present with any flattening or deviation of the ventricular septum toward the left ventricle.
Among the 4 participants, there was 83.9% agreement on the presence or absence of RV enlargement (κ = 0.84), 74.2% agreement on the presence or absence of RV systolic dysfunction (κ = 0.69), and 71.0% agreement on the presence or absence of septal deviation (κ = 0.59). Intraobserver agreement was 100% for each RV dysfunction variable for each observer (κ = 1.0).
Agreement was substantial for both severe RV enlargement and RV systolic dysfunction and moderate for septal deviation. Right ventricular dysfunction assessment with qualitative goal-directed echocardiographic criteria is reproducible for PE risk stratification.
使用定性的目标导向超声心动图标准评估亚大面积肺栓塞(PE)患者右心室(RV)功能障碍预后的观察者间一致性。
两名急诊科医生和两名心脏病专家独立审查了31组目标导向超声心动图视频片段,这些片段由急诊科医生从血压正常的PE患者中获取,包括至少3个窗口的图像。重复观察9组片段以评估观察者内一致性。目标导向超声心动图检查右心室功能障碍的标准如下:存在右心室扩大,右心室与左心室基底直径比为1.0或更高,且在2个或更多不同窗口中右心室心尖变钝;如果三尖瓣环向心尖移动10mm或更少且右心室游离壁运动减弱,则存在右心室收缩功能障碍;存在室间隔偏移,表现为室间隔向左侧心室任何程度的扁平或偏移。
在4名参与者中,对于右心室扩大的存在与否,一致性为83.9%(κ = 0.84);对于右心室收缩功能障碍的存在与否,一致性为74.2%(κ = 0.69);对于室间隔偏移的存在与否,一致性为71.0%(κ = 0.59)。每个观察者对每个右心室功能障碍变量的观察者内一致性均为100%(κ = 1.0)。
对于严重右心室扩大和右心室收缩功能障碍,一致性较高;对于室间隔偏移,一致性中等。使用定性的目标导向超声心动图标准评估右心室功能障碍对PE风险分层具有可重复性。