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肺栓塞患者经超声心动图对右心室功能障碍进行定性评估时的观察者间及观察者内一致性

Interobserver and Intraobserver Agreement on Qualitative Assessments of Right Ventricular Dysfunction With Echocardiography in Patients With Pulmonary Embolism.

作者信息

Weekes Anthony J, Oh Laura, Thacker Gregory, Johnson Angela K, Runyon Michael, Rose Geoffrey, Johnson Thomas, Templin Megan, Norton H James

机构信息

Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina USA

Emory University, Atlanta, Georgia USA.

出版信息

J Ultrasound Med. 2016 Oct;35(10):2113-20. doi: 10.7863/ultra.15.11007. Epub 2016 Aug 8.

Abstract

OBJECTIVES

To evaluate observer agreement using qualitative goal-directed echocardiographic criteria for right ventricular (RV) dysfunction prognostication in submassive pulmonary embolism (PE).

METHODS

Two emergency physicians and 2 cardiologists independently reviewed 31 packets of goal-directed echocardiographic video clips consisting of at least 3 windows obtained by emergency physicians from normotensive patients with PE. Nine packets were repeated to assess for intraobserver agreement. Right ventricular dysfunction criteria on goal-directed echocardiography were as follows: RV enlargement was present, with a right-to-left ventricular basal diameter ratio of 1.0 or higher and blunting of the apex of the RV in 2 or more different windows; RV systolic dysfunction was present if the tricuspid annulus moved toward the apex 10 mm or less and there was RV free wall hypokinesis; and septal deviation was present with any flattening or deviation of the ventricular septum toward the left ventricle.

RESULTS

Among the 4 participants, there was 83.9% agreement on the presence or absence of RV enlargement (κ = 0.84), 74.2% agreement on the presence or absence of RV systolic dysfunction (κ = 0.69), and 71.0% agreement on the presence or absence of septal deviation (κ = 0.59). Intraobserver agreement was 100% for each RV dysfunction variable for each observer (κ = 1.0).

CONCLUSIONS

Agreement was substantial for both severe RV enlargement and RV systolic dysfunction and moderate for septal deviation. Right ventricular dysfunction assessment with qualitative goal-directed echocardiographic criteria is reproducible for PE risk stratification.

摘要

目的

使用定性的目标导向超声心动图标准评估亚大面积肺栓塞(PE)患者右心室(RV)功能障碍预后的观察者间一致性。

方法

两名急诊科医生和两名心脏病专家独立审查了31组目标导向超声心动图视频片段,这些片段由急诊科医生从血压正常的PE患者中获取,包括至少3个窗口的图像。重复观察9组片段以评估观察者内一致性。目标导向超声心动图检查右心室功能障碍的标准如下:存在右心室扩大,右心室与左心室基底直径比为1.0或更高,且在2个或更多不同窗口中右心室心尖变钝;如果三尖瓣环向心尖移动10mm或更少且右心室游离壁运动减弱,则存在右心室收缩功能障碍;存在室间隔偏移,表现为室间隔向左侧心室任何程度的扁平或偏移。

结果

在4名参与者中,对于右心室扩大的存在与否,一致性为83.9%(κ = 0.84);对于右心室收缩功能障碍的存在与否,一致性为74.2%(κ = 0.69);对于室间隔偏移的存在与否,一致性为71.0%(κ = 0.59)。每个观察者对每个右心室功能障碍变量的观察者内一致性均为100%(κ = 1.0)。

结论

对于严重右心室扩大和右心室收缩功能障碍,一致性较高;对于室间隔偏移,一致性中等。使用定性的目标导向超声心动图标准评估右心室功能障碍对PE风险分层具有可重复性。

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