Madhuvanthi M, Lathadevi G V
Junior Resident, Department of Physiology, PSG Institute of Medical Sciences and Research (PSGIMS & R) , Coimbatore, India .
Professor, Department of Physiology, PSG Institute of Medical Sciences and Research (PSGIMS & R) , Coimbatore, India .
J Clin Diagn Res. 2016 Jun;10(6):CC05-7. doi: 10.7860/JCDR/2016/18278.8047. Epub 2016 Jun 1.
Serum proteins are an important indicator of the nutritional status in an individual. There is a worldwide prevalence of both undernourishment and obesity. It has been suggested that low Body Mass Index (BMI) is associated with a decrease in serum protein levels predisposing them to other illnesses. Overweight and obese individuals carry risk for various other non-communicable diseases.
To compare the serum protein levels in underweight, overweight and obese individuals with that of normal body mass index individuals.
This prospective study was conducted in subjects who attended the master health checkup clinic of PSG hospitals. Subjects in the age group of 20-50 years were selected. Their serum proteins and BMI was measured. Twenty subjects each of underweight, normal, overweight and obese individuals were selected, categorized and compared.
The serum protein level of normal individuals (Group I) was compared with underweight (Group II), overweight (Group III) and obese subjects (Group IV) by one-way ANOVA analysis. The mean serum total proteins in gm/dl in group I controls was 7.555±0.37 compared to Group II (underweight) which was 7.295±0.419. Low BMI was found to be associated with a decrease in serum protein level which was not statistically significant. Elevated BMI as in overweight and obese subjects showed no significant alterations in serum protein levels with p >0.05 and the changes were found to be independent of the body mass index.
Underweight individuals showed a decrease in serum protein levels whereas there were no significant changes in the serum protein levels in overweight and obese individuals.
血清蛋白是个体营养状况的重要指标。全球范围内都存在营养不良和肥胖问题。有人提出，低体重指数（BMI）与血清蛋白水平降低有关，这使个体更容易患其他疾病。超重和肥胖个体面临各种其他非传染性疾病的风险。
比较体重过轻、超重和肥胖个体与正常体重指数个体的血清蛋白水平。
这项前瞻性研究在参加PSG医院主健康检查诊所的受试者中进行。选择年龄在20至50岁之间的受试者。测量他们的血清蛋白和BMI。分别选择20名体重过轻、正常、超重和肥胖的个体，进行分类和比较。
通过单因素方差分析将正常个体（第一组）的血清蛋白水平与体重过轻（第二组）、超重（第三组）和肥胖受试者（第四组）进行比较。第一组对照组的血清总蛋白平均水平为7.555±0.37克/分升，而第二组（体重过轻）为7.295±0.419克/分升。发现低BMI与血清蛋白水平降低有关，但无统计学意义。超重和肥胖受试者中升高的BMI在血清蛋白水平上无显著变化，p>0.05，且发现这些变化与体重指数无关。
体重过轻的个体血清蛋白水平降低，而超重和肥胖个体的血清蛋白水平无显著变化。
