Severe microvascular disease in type II diabetes of early onset. A family study.
作者信息
Scalvini T, Spandrio S, di Stefano O, Cotelli M C, Carella G, Balestrieri G P
机构信息
Cattedra di Patologia Medica, Università di Brescia, II Divisione di Medicina, Spedali di Brescia, Italy.
出版信息
Acta Diabetol Lat. 1989 Jan-Mar;26(1):58-74. doi: 10.1007/BF02581198.
PMID:2750446
Abstract
Both early onset and late onset type II diabetes were present in one family of nine siblings. The three early onset type II diabetic siblings showed severe microvascular complications: proliferative retinopathy, diabetic nephropathy, and peripheral neuropathy. Early onset type II diabetes was not associated with any particular HLA haplotype. Early onset type II diabetes could be considered a clinical and genetic disease entity different from MODY type diabetes.
摘要
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