Institute for Cell Biology, University of Bonn, Bonn, Germany.
Curr Biol. 2016 Aug 8;26(15):R703-R705. doi: 10.1016/j.cub.2016.06.017.
Recent publications illustrate an extensive crosstalk between the actin cytoskeleton and autophagy, a program for self-digestion. Actin polymerization provides a pushing force for organelle shaping and trafficking during autophagy, but the cytoskeleton is also targeted by autophagy under mechanical strain.
最近的出版物表明,肌动蛋白细胞骨架和自噬之间存在广泛的交流,自噬是一种自我消化的程序。肌动蛋白聚合为自噬过程中细胞器的形成和运输提供了推力,但在机械应变下,细胞骨架也是自噬的靶点。