Institute of Science and Technology Austria (IST Austria), am Campus 1, 3400 Klosterneuburg, Austria.
Institute of Science and Technology Austria (IST Austria), am Campus 1, 3400 Klosterneuburg, Austria.
Curr Biol. 2017 Jan 9;27(1):R24-R25. doi: 10.1016/j.cub.2016.11.035.
Coordinated changes of cell shape are often the result of the excitable, wave-like dynamics of the actin cytoskeleton. New work shows that, in migrating cells, protrusion waves arise from mechanochemical crosstalk between adhesion sites, membrane tension and the actin protrusive machinery.
细胞形状的协调变化通常是肌动蛋白细胞骨架的兴奋、波动动力学的结果。新的研究表明，在迁移细胞中，突起波源于粘附位点、膜张力和肌动蛋白伸出机制之间的力学化学串扰。
