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中国人群孔源性视网膜脱离后脉络膜脱离的危险因素

Risk factors for choroidal detachment following rhegmatogenous retinal detachment in a chinese population.

作者信息

Yu Yajie, An Ming, Mo Bin, Yang Zhen, Liu Wu

机构信息

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, 100730, China.

Department of Ophthalmology, Qingdao Municipal Hospital, Qingdao, Shandong, 266011, China.

出版信息

BMC Ophthalmol. 2016 Aug 9;16:140. doi: 10.1186/s12886-016-0319-9.

Abstract

BACKGROUD

Choroidal detachment (CD) following primary rhegmatogenous retinal detachment (RRD) is a special type of RRD. The purpose of this study is to investigate the potential risk factors of RRD with CD in a Chinese population.

METHODS

All of 201 consecutive RRD with CD patients and 210 RRD without CD patients were enrolled in this case-control retrospective study. The clinical data from these cases were reviewed here. Patients were undergone scleral buckling or encircling or both, or pars plana vitrectomy with or without scleral buckling or encircling or both according the patients' condition. The incidence of RRD with CD in this Chinese population was measured, and the potential risk factors for the development of RRD with CD were investigated by multivariate logistic regression analysis.

RESULTS

In this population, the incidence of RRD with CD was 8.6 %. The incidence of RRD with CD was significantly higher in patients with macular hole (P < 0.05), retinal breaks located posterior to the equator (P < 0.05), and total detachment (P < 0.05). Furthermore, the incidence of RRD with CD was significantly higher in patients with longer axial length (P < 0.05) only when ages, IOP, AL and duration time was set for categorical variables.

CONCLUSIONS

Hypotony, retinal breaks located posteriorly especially macular hole, longer axial length, and the whole retinal detachment might be the potential risk factors for the development of CD in RRD patients.

摘要

背景

原发性孔源性视网膜脱离(RRD)后发生的脉络膜脱离(CD)是RRD的一种特殊类型。本研究旨在探讨中国人群中RRD合并CD的潜在危险因素。

方法

本病例对照回顾性研究纳入了201例连续的RRD合并CD患者和210例RRD不合并CD患者。回顾了这些病例的临床资料。根据患者情况,对患者进行巩膜扣带术或环扎术或两者联合,或进行玻璃体切割术联合或不联合巩膜扣带术或环扎术或两者联合。测量了该中国人群中RRD合并CD的发生率,并通过多因素logistic回归分析研究了RRD合并CD发生的潜在危险因素。

结果

在该人群中,RRD合并CD的发生率为8.6%。黄斑裂孔患者(P<0.05)、赤道后视网膜裂孔患者(P<0.05)和全脱离患者(P<0.05)中RRD合并CD的发生率显著更高。此外,仅当将年龄、眼压、眼轴长度和病程时间设定为分类变量时,眼轴长度较长的患者中RRD合并CD的发生率显著更高(P<0.05)。

结论

低眼压、后部视网膜裂孔尤其是黄斑裂孔、较长的眼轴长度以及全视网膜脱离可能是RRD患者发生CD的潜在危险因素。

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