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经巩膜睫状体光凝联合曲安奈德治疗新生血管性青光眼的临床研究 --- 请注意,这只是一个可能的译文,具体的翻译结果可能因语境和专业术语而有所不同。

Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study.

机构信息

Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh; Department of Ophthalmology, Hind Institute of Medical Sciences, Sitapur, Uttar Pradesh, India.

Department of Vitreo-retina and Uveitis, Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.

出版信息

Indian J Ophthalmol. 2022 Apr;70(4):1302-1306. doi: 10.4103/ijo.IJO_1788_21.

Abstract

PURPOSE

To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD).

METHODS

This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD.

RESULTS

The mean age of the cohort was 53.8 ± 10.8 years (range: 39-72 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02-9.42 mm). Following SCTA, a successful response (>50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications.

CONCLUSION

Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD.

摘要

目的

研究术前玻璃体内曲安奈德(SCTA)在实现与孔源性视网膜脱离(RRD)相关的浆液性脉络膜脱离(CD)消退/缓解中的安全性和有效性。

方法

这是一项前瞻性、非对照、干预性初步研究。所有伴有 CD 的 RD 患者均在接受玻璃体切除术/巩膜扣带术前行玻璃体内 SCTA 注射。连续进行超声 B 扫描以评估 CD 高度的变化。

结果

队列的平均年龄为 53.8 ± 10.8 岁(范围:39-72 岁)。CD 存在于中位数 3 个象限中;累积平均 CD 高度为 5.59 毫米(范围:2.02-9.42 毫米)。在 SCTA 后,3 天内 5 只眼有成功反应(>50%的减少),5 天内 2 只眼有成功反应。3 只眼对 SCTA 无反应,在进行玻璃体切除术前需要手术引流。未观察到术中注射相关并发症。1 只眼在玻璃体切除术后出现短暂的眼压升高(30mmHg),经局部抗青光眼药物治疗成功控制。

结论

玻璃体内给予曲安奈德似乎是一种安全有效的技术,可实现 RRD 眼中 CD 的消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182f/9240553/40e1fc795205/IJO-70-1302-g001.jpg

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