Snyder S W, Cardwell M S
Department of Obstetrics and Gynecology, University of Missouri Health Sciences Center, Columbia 65212.
Am J Obstet Gynecol. 1989 Jul;161(1):35-6. doi: 10.1016/0002-9378(89)90226-3.
A patient who received tocolysis with nifedipine developed neuromuscular blockade after 500 mg of magnesium sulfate was administered. This reaction demonstrates that nifedipine can seriously potentiate the toxicity of magnesium. Caution should be exercised when these two tocolytics are combined.
一名接受硝苯地平保胎治疗的患者在静脉注射500mg硫酸镁后出现了神经肌肉阻滞。该反应表明硝苯地平可严重增强镁的毒性。联合使用这两种保胎药物时应谨慎。