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关于HIV感染者外周血中促炎细胞因子白细胞介素-1β、白细胞介素-17和白细胞介素-6的数据。

Data on pro-inflammatory cytokines IL-1β, IL-17, and IL-6 in the peripheral blood of HIV-infected individuals.

作者信息

Saing Tommy, Valdivia Anddre, Hussain Parveen, Ly Judy, Gonzalez Leslie, Guilford Frederick T, Pearce Daniel, Venketaraman Vishwanath

机构信息

Graduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.

Your Energy System, Palo Alto, CA, USA.

出版信息

Data Brief. 2016 Jul 19;8:1044-7. doi: 10.1016/j.dib.2016.07.023. eCollection 2016 Sep.

DOI:10.1016/j.dib.2016.07.023
PMID:27508262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4969237/
Abstract

Our most recent data indicate differences in the levels of pro-inflammatory cytokines (IL-1β, IL-17, and IL-6) and malondialdehyde (MDA), a stable end-product of lipid peroxidation in the plasma samples between HIV positive individuals with low CD4 T cell counts <200 mm(3) and HIV positive individuals with CD4 T cell counts between 200 and 300 mm(3) (ee). The data lend support and provide valuable correlation between CD4 T cell counts and the levels of inflammatory cytokines in HIV positive individuals.

摘要

我们最近的数据表明,血浆样本中促炎细胞因子(白细胞介素-1β、白细胞介素-17和白细胞介素-6)和丙二醛(MDA,脂质过氧化的稳定终产物)的水平在CD4 T细胞计数<200/mm³的HIV阳性个体与CD4 T细胞计数在200至300/mm³之间的HIV阳性个体之间存在差异(见图)。这些数据为HIV阳性个体中CD4 T细胞计数与炎性细胞因子水平之间提供了支持并建立了有价值的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1188/4969237/5ccf50bb0881/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1188/4969237/aa2cba47f147/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1188/4969237/5ccf50bb0881/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1188/4969237/aa2cba47f147/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1188/4969237/5ccf50bb0881/gr2.jpg

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