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免疫分枝杆菌新鉴定的T细胞抗原的人类白细胞抗原(HLA)结合表位数据集。

Human leukocyte antigen (HLA)-binding epitopes dataset for the newly identified T-cell antigens of Mycobacterium immunogenum.

作者信息

Chandra Harish, Yadav Jagjit S

机构信息

Microbial Pathogenesis and Toxicogenomics Laboratory, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0056, United States of America.

出版信息

Data Brief. 2016 Jul 5;8:1069-71. doi: 10.1016/j.dib.2016.06.045. eCollection 2016 Sep.

Abstract

The dataset described herein is related to our article entitled "T-cell antigens of Mycobacterium immunogenum (MI), an etiological agent of occupational hypersensitivity pneumonitis'' (Chandra and Yadav, 2016) [1]. The data include in silico-predicted T-cell epitopes of the T-cell antigens AgA and AgD of MI predicted to bind to HLA-I or HLA-II alleles. Data on two reference T-cell antigens ESAT-6 and CFP-10 of Mycobacterium tuberculosis H37Rv are included for comparison. The data for each antigen include the predicted epitope׳s amino acid sequence, its first amino acid position, and its ability to bind HLA-I or HLA-II allele(s).

摘要

本文所述数据集与我们发表的题为《免疫原性分枝杆菌(MI)的T细胞抗原,职业性超敏性肺炎的病原体》(钱德拉和亚达夫,2016年)[1]的文章相关。数据包括对MI的T细胞抗原AgA和AgD进行计算机模拟预测的、预计可与HLA - I或HLA - II等位基因结合的T细胞表位。还纳入了结核分枝杆菌H37Rv的两种参考T细胞抗原ESAT - 6和CFP - 10的数据用于比较。每种抗原的数据包括预测表位的氨基酸序列、其首个氨基酸位置以及与HLA - I或HLA - II等位基因结合的能力。

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