Singh H, Raghava G P
Bioinformatics Centre, Institute of Microbial Technology, Sector 39A, Chandigarh-160036, India.
Bioinformatics. 2001 Dec;17(12):1236-7. doi: 10.1093/bioinformatics/17.12.1236.
ProPred is a graphical web tool for predicting MHC class II binding regions in antigenic protein sequences. The server implement matrix based prediction algorithm, employing amino-acid/position coefficient table deduced from literature. The predicted binders can be visualized either as peaks in graphical interface or as colored residues in HTML interface. This server might be a useful tool in locating the promiscuous binding regions that can bind to several HLA-DR alleles.
The server is available at http://www.imtech.res.in/raghava/propred/
ProPred是一种用于预测抗原蛋白序列中MHC II类结合区域的图形化网络工具。该服务器实现了基于矩阵的预测算法，采用从文献中推导出来的氨基酸/位置系数表。预测的结合物可以在图形界面中显示为峰，也可以在HTML界面中显示为彩色残基。该服务器可能是定位可与多个HLA-DR等位基因结合的混杂结合区域的有用工具。
该服务器可在http://www.imtech.res.in/raghava/propred/获取。
