Papadavid E, Katsimbri P, Kapniari I, Koumaki D, Karamparpa A, Dalamaga M, Tzannis K, Βoumpas D, Rigopoulos D
2nd Department of Dermatology and Venereology, University of Athens, Attikon General Hospital, Chaidari, Greece.
4th Department of Internal Medicine, University of Athens, Attikon General Hospital, Chaidari, Greece.
J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1749-1752. doi: 10.1111/jdv.13700. Epub 2016 Aug 10.
To evaluate the prevalence and its clinical characteristics of psoriatic arthritis (PsA) in a specialized psoriasis clinic of a University Hospital.
In this retrospective study, 278 patients with psoriasis were evaluated between 2011 and 2013.
The study included 278 patients with psoriasis: 144 (52%) were male and 134 (48%) female. Their median age was 51.41 with median psoriasis presenting age of 34.52 years. Referring to the type of psoriasis, 86% presented with plaque psoriasis, 5% guttate, 2% palms and soles, 2% inverse, 1% pustular and 4% with psoriasis of more than one type. Nail disease appeared in 121 patients (43.5%) and scalp disease in 175 (63%). Of these patients, 85 (30%) had PsA, whereas 51% of patients with PsA had psoriatic nail disease. With reference to the PsA type, 43 (51%) patients presented with polyarthritis, 10 (12%) with oligoarthritis, 7 (8%) with axial arthritis, whereas the rest 25 of them (31%) had PsA of more than one type. The subgroup of patients with PsA had significantly higher rates of comorbidities including arterial hypertension, diabetes and hypercholesterolaemia compared to non-PsA patients with 41% vs. 17% (P = 0.001), 20% vs. 8% (P = 0.021) and 41% vs. 19% (P = 0.004), respectively.
The prevalence of PsA among patients with psoriasis was relatively higher in Greece compared to other ethnic-based studies. Comorbidities related to life expectancy were more frequent. As there is a high percentage of undiagnosed cases with active arthritis among patients with psoriasis, dermatologists should be aware of PsA clinical signs in order to recognize it earlier and provide successful treatment.
评估某大学医院专科银屑病门诊中银屑病关节炎（PsA）的患病率及其临床特征。
在这项回顾性研究中，于2011年至2013年期间对278例银屑病患者进行了评估。
该研究纳入278例银屑病患者，其中男性144例（52%），女性134例（48%）。他们的中位年龄为51.41岁，银屑病发病的中位年龄为34.52岁。就银屑病类型而言，86%为斑块状银屑病，5%为点滴状，2%为掌跖部，2%为反向性，1%为脓疱型，4%为多种类型并存。121例患者（43.5%）出现甲病，175例（63%）出现头皮病变。在这些患者中，85例（30%）患有PsA，而PsA患者中有51%患有银屑病甲病。就PsA类型而言，43例（51%）患者表现为多关节炎，10例（12%）为少关节炎，7例（8%）为轴性关节炎，其余25例（31%）为多种类型并存的PsA。与非PsA患者相比，PsA患者亚组的合并症发生率显著更高，包括动脉高血压、糖尿病和高胆固醇血症，分别为41%对17%（P = 0.001）、20%对8%（P = 0.021）和41%对19%（P = 0.004）。
与其他基于种族的研究相比，希腊银屑病患者中PsA的患病率相对较高。与预期寿命相关的合并症更为常见。由于银屑病患者中存在较高比例的未诊断出的活动性关节炎病例，皮肤科医生应了解PsA的临床体征，以便更早地识别并提供成功的治疗。
