Odom Stephen R, Howell Michael D, Gupta Alok, Silva George, Cook Charles H, Talmor Daniel
Department of Surgery, Division of Acute Care Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Division of Pulmonary, Critical Care, and Sleep Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.
J Emerg Trauma Shock. 2016 Jul-Sep;9(3):103-6. doi: 10.4103/0974-2700.185272.
We noted a bimodal relationship between mortality and shock index (SI), the ratio of heart rate to systolic blood pressure.
To determine if extremes of SI can predict mortality in trauma patients.
Retrospective evaluation of adult trauma patients at a tertiary care center from 2000 to 2012 in the United States.
We examined the SI in trauma patients and determined the adjusted mortality for patients with and without head injuries.
Descriptive statistics and multivariable logistic regression.
SI values demonstrated a U-shaped relationship with mortality. Compared with patients with a SI between 0.5 and 0.7, patients with a SI of <0.3 had an odds ratio for death of 2.2 (95% confidence interval [CI] 21.2-4.1) after adjustment for age, Glasgow Coma score, and injury severity score while patients with SI >1.3 had an odds ratio of death of 3.1. (95% CI 1.6-5.9). Elevated SI is associated with increased mortality in patients with isolated torso injuries, and is associated with death at both low and high values in patients with head injury.
Our data indicate a bimodal relationship between SI and mortality in head injured patients that persists after correction for various co-factors. The distribution of mortality is different between head injured patients and patients without head injuries. Elevated SI predicts death in all trauma patients, but low SI values only predict death in head injured patients.
我们注意到死亡率与休克指数(SI,心率与收缩压之比)之间存在双峰关系。
确定SI的极端值是否可预测创伤患者的死亡率。
对2000年至2012年在美国一家三级护理中心的成年创伤患者进行回顾性评估。
我们检查了创伤患者的SI,并确定了有无头部损伤患者的校正死亡率。
描述性统计和多变量逻辑回归。
SI值与死亡率呈U形关系。与SI在0.5至0.7之间的患者相比,SI<0.3的患者在调整年龄、格拉斯哥昏迷评分和损伤严重程度评分后,死亡比值比为2.2(95%置信区间[CI]21.2 - 4.1),而SI>1.3的患者死亡比值比为3.1(95%CI 1.6 - 5.9)。SI升高与单纯躯干损伤患者的死亡率增加相关,在头部损伤患者中,SI低值和高值均与死亡相关。
我们的数据表明,在对各种协变量进行校正后,头部损伤患者的SI与死亡率之间存在双峰关系。头部损伤患者和无头部损伤患者的死亡率分布不同。SI升高可预测所有创伤患者的死亡,但SI低值仅能预测头部损伤患者的死亡。