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休克指数作为创伤患者严重损伤的标志物。

Shock index as a marker for significant injury in trauma patients.

作者信息

King R W, Plewa M C, Buderer N M, Knotts F B

机构信息

St. Vincent Medical Center, Toledo Hospital Emergency Medicine Residency Program, OH 43608, USA.

出版信息

Acad Emerg Med. 1996 Nov;3(11):1041-5. doi: 10.1111/j.1553-2712.1996.tb03351.x.

Abstract

OBJECTIVE

To determine whether the shock index (SI), defined as the ratio of heart rate (HR) to systolic blood pressure (SBP), is a useful marker for significant injury in trauma patients.

METHODS

A retrospective database analysis was used to relate the SI to the clinical measures: death within 24 hours, injury severity score (ISS) > or = 16, intensive care unit (ICU) stay > or = 1 day, and amount of blood transfused (BT) > or = 2 units. Consecutive trauma patients seen at one level I trauma center over a 24-month period were reviewed; excluded were patients not requiring trauma team consultation, or those with either incomplete records, severe head injury (Glasgow Coma Scale score < or = 8), or age < 14 years. The SI was calculated from ED admission vital signs. Receiver operating characteristic (ROC) curves were used to find the value of the SI that maximized the sum of sensitivity and specificity for predicting each measure, separately; a separate analysis was done to determine the optimal SI threshold for predicting any of the severity measures.

RESULTS

1,101 cases met study criteria. The optimal SI values (by ROC analysis) for predicting the severity measures were: 1.10 for death < 24 hours, 0.71 for ISS > or = 16, 0.77 for ICU > or = 1 day, and 0.85 for BT > or = 2 units. The optimal SI value (by ROC analysis) for any of the above measures was 0.83; use of this SI cutoff provided a sensitivity of 37% (95% CI 32-42%), a specificity of 83% (95% CI 80-87%), and a negative predictive value of 58% (95% CI 54-61%) for any measure. This SI threshold predicted between 24% fewer cases and 4% more cases of poor outcome than did the optimal thresholds HR and SBP, respectively.

CONCLUSION

The optimal SI threshold performed similarly to the optimal threshold HR or SBP for prediction of injury severity.

摘要

目的

确定定义为心率(HR)与收缩压(SBP)之比的休克指数(SI)是否为创伤患者严重损伤的有用标志物。

方法

采用回顾性数据库分析将SI与临床指标相关联:24小时内死亡、损伤严重程度评分(ISS)≥16、重症监护病房(ICU)住院≥1天以及输血量(BT)≥2单位。回顾了在一个一级创伤中心24个月期间连续就诊的创伤患者;排除了不需要创伤团队会诊的患者,或记录不完整、重度颅脑损伤(格拉斯哥昏迷量表评分≤8)或年龄<14岁的患者。SI根据急诊入院生命体征计算。采用受试者操作特征(ROC)曲线分别找出预测各指标时使灵敏度和特异度之和最大化的SI值;进行单独分析以确定预测任何严重程度指标的最佳SI阈值。

结果

1101例符合研究标准。预测严重程度指标的最佳SI值(通过ROC分析)分别为:24小时内死亡为1.10,ISS≥16为0.71,ICU住院≥1天为0.77,BT≥2单位为0.85。上述任何一项指标的最佳SI值(通过ROC分析)为0.83;采用此SI临界值对任何指标的灵敏度为37%(95%可信区间32 - 42%),特异度为83%(95%可信区间80 - 87%),阴性预测值为58%(95%可信区间54 - 61%)。与最佳阈值HR和SBP相比,此SI阈值预测不良结局的病例数分别少24%和多4%。

结论

最佳SI阈值在预测损伤严重程度方面与最佳阈值HR或SBP表现相似。

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