Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Cell Res. 2016 Sep;26(9):973-4. doi: 10.1038/cr.2016.96. Epub 2016 Aug 12.
Astrocytes are emerging as essential regulators of brain metastasis progression. In a current issue of Nature, Chen et al. identify a novel mechanism of astrocyte-carcinoma interaction and exploit vulnerabilities therein to slow brain metastatic growth in pre-clinical models.
星形细胞正在成为脑转移进展的重要调节者。在本期《自然》杂志上，Chen 等人发现了星形细胞-癌细胞相互作用的新机制，并利用其中的脆弱性在临床前模型中减缓脑转移的生长。
