Department of Colorectal Surgery, Queen Elizabeth Hospital, Gateshead, NE9 6SX, UK.
Br J Surg. 2016 Oct;103(11):1557-65. doi: 10.1002/bjs.10261. Epub 2016 Aug 12.
The weekend effect describes excess mortality associated with hospital admission on Saturday or Sunday. This study assessed whether a weekend effect exists for patients admitted for emergency general surgery.
Data for emergency general surgical admissions to National Health Service hospitals in the Northern Deanery in England between 2000 and 2014 were collected, including demographics, co-morbidities, diagnoses, operations undertaken and outcomes. The primary outcome of interest was in-hospital death within 30 days of admission. Cox regression analysis was undertaken with adjustment for co-variables.
There were 12 100 in-hospital deaths within 30 days of admission (3·3 per cent). The overall 30-day mortality rate reduced significantly during the 15-year interval studied, from 5·4 per cent (2000-2004) to 4·0 per cent (2005-2009) and 2·9 per cent during 2010-2014 (P < 0·001). There was no significant mortality difference for patients admitted at the weekend in adjusted Cox models (hazard ratio (HR) 1·00 for Saturday and 0·90 for Sunday, versus Wednesday). There was a significantly higher mortality for operations undertaken at the weekend (HR 1·15 for Saturday and 1·40 for Sunday; P = 0·021 and P < 0·001 respectively). The significantly increased mortality that was evident for emergency surgery at the weekend compared with weekdays in 2000-2004 (HR 1·46 for Saturday and 1·55 for Sunday; both P < 0·001); had reduced by 2010-2014, when the adjusted mortality risk was not significant (HR 1·18 for Saturday and 1·12 for Sunday).
During the past 15 years there has been a weekend effect in patients undergoing emergency general surgery based on day of operation, but not day of admission. Overall mortality for emergency general surgery has improved significantly, and in the past 5 years the increased mortality risk of weekend surgery has reduced.
“周末效应”描述了星期六或星期天住院与死亡率升高之间的关系。本研究评估了接受紧急普通外科治疗的患者是否存在“周末效应”。
收集了 2000 年至 2014 年期间英格兰北部教区内国民保健署医院接受紧急普通外科治疗的患者数据,包括人口统计学资料、合并症、诊断、手术和结果。主要观察指标为入院后 30 天内院内死亡。采用 Cox 回归分析调整协变量。
入院后 30 天内共有 12100 例院内死亡(3.3%)。在 15 年的研究期间,总体 30 天死亡率显著下降,从 2000-2004 年的 5.4%降至 2005-2009 年的 4.0%和 2010-2014 年的 2.9%(P<0.001)。在调整后的 Cox 模型中,周末入院的患者死亡率没有显著差异(星期六的危险比为 1.00,星期日为 0.90,与星期三相比)。周末进行的手术死亡率显著升高(星期六为 1.15,星期日为 1.40;P=0.021 和 P<0.001)。与 2000-2004 年相比,周末接受紧急手术的患者死亡率显著升高(星期六为 1.46,星期日为 1.55;均 P<0.001);到 2010-2014 年,调整后的死亡率风险不显著(星期六为 1.18,星期日为 1.12)。
在过去的 15 年中,根据手术日期而非入院日期,接受紧急普通外科手术的患者存在“周末效应”。紧急普通外科手术的总体死亡率显著提高,过去 5 年周末手术的死亡率风险增加已有所降低。