术中使用10%去氧肾上腺素的不良反应：病例报告
Adverse effect of intraoperative phenylephrine 10%: case report.
作者信息
Lai Y K
机构信息
Department of Ophthalmology, Faculty of Medicine, University of Malaya, Malaysia.
出版信息
Br J Ophthalmol. 1989 Jun;73(6):468-9. doi: 10.1136/bjo.73.6.468.
Abstract
The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease.
摘要
本文报告了一例患者，该患者可能因去氧肾上腺素用药过量而出现严重急性高血压、心律失常和心肌梗死。手术期间滴注该药可能增强了大量药物的全身吸收。因此，手术期间使用该药应谨慎，尤其是老年患者和患有心血管疾病的患者。
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本文引用的文献
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Hazards of the use of sympathomimetic drugs in ophthalmology.
AMA Arch Ophthalmol. 1956 Aug;56(2):176-9. doi: 10.1001/archopht.1956.00930040184003.
2
Possible adverse effects from topical ocular 10% phenylephrine.局部使用10%去氧肾上腺素可能产生的不良反应。
Am J Ophthalmol. 1978 Apr;85(4):447-53. doi: 10.1016/s0002-9394(14)75239-0.
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