Lai Y K
Department of Ophthalmology, Faculty of Medicine, University of Malaya, Malaysia.
Br J Ophthalmol. 1989 Jun;73(6):468-9. doi: 10.1136/bjo.73.6.468.
The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease.
本文报告了一例患者，该患者可能因去氧肾上腺素用药过量而出现严重急性高血压、心律失常和心肌梗死。手术期间滴注该药可能增强了大量药物的全身吸收。因此，手术期间使用该药应谨慎，尤其是老年患者和患有心血管疾病的患者。
