多个表达的内源性脑胶质瘤表位作为脑胶质瘤的新型疫苗。
Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas.
机构信息
Department of Neurosurgery, The Cancer Biology and The Immunology Graduate Programs, The Cancer Center, The University of Michigan School of Medicine, Ann Arbor, Michigan. Department of Cell and Developmental Biology, The University of Michigan School of Medicine, Ann Arbor, Michigan.
出版信息
Clin Cancer Res. 2016 Oct 1;22(19):4760-4762. doi: 10.1158/1078-0432.CCR-16-1477. Epub 2016 Aug 12.
A novel approach to immunization against glioma tumors is described. Immunization against 11 antigens expressed in malignant brain tumors elicits responses to one or more antigens in a large percentage of patients. This novel approach suggests that it could be extended to a phase III trial. Clin Cancer Res; 22(19); 4760-2. ©2016 AACRSee related article by Rampling et al., p. 4776.
一种针对神经胶质瘤肿瘤的新型免疫接种方法被描述。针对恶性脑肿瘤中表达的 11 种抗原进行免疫接种，可使很大一部分患者对一种或多种抗原产生应答。这种新方法表明，它可以扩展到 III 期试验。临床癌症研究；22（19）；4760-2. ©2016AACR 见 Rampling 等人的相关文章，第 4776 页。
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