Foroughi Firoozeh, Hassanzadeh-Tabrizi S A, Bigham Ashkan
Young Researchers and Elite Club, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Young Researchers and Elite Club, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:774-779. doi: 10.1016/j.msec.2016.07.028. Epub 2016 Jul 14.
In this study, an innovative synthesis process has been developed to produce hydroxyapatite-magnesium ferrite (HA-MgFe2O4) nanocomposite. In addition, the effect of calcination temperature on drug delivery behavior of produced samples was investigated. HA-MgFe2O4 nanocomposite was prepared via one-step modified reverse microemulsion synthesis route. The resulting products were characterized by X-ray Diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), and Brunauer-Emmett-Teller surface area analysis (BET). The calcined samples at 500 and 700°C demonstrated mesoporous characteristics and large specific surface areas of 88 and 32m(2)/g, respectively. TEM and VSM results showed that the nanocomposite calcined at 700°C has core-shell morphology and a maximum saturation magnetization of 9.47emug(-1).
在本研究中，已开发出一种创新的合成工艺来制备羟基磷灰石-镁铁氧体（HA-MgFe2O4）纳米复合材料。此外，还研究了煅烧温度对所制备样品药物递送行为的影响。HA-MgFe2O4纳米复合材料通过一步改性反相微乳液合成路线制备。所得产物通过X射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、场发射扫描电子显微镜（FESEM）、透射电子显微镜（TEM）、振动样品磁强计（VSM）和布鲁诺尔-埃米特-泰勒表面积分析（BET）进行表征。在500和700°C煅烧的样品分别表现出介孔特性和88和32m(2)/g的大比表面积。TEM和VSM结果表明，在700°C煅烧的纳米复合材料具有核壳形态，最大饱和磁化强度为9.47emug(-1)。
