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术前经皮经胸针吸活检增加了胸膜下纯实性结节的病理I期肺癌患者胸膜复发的风险。

Preoperative Percutaneous Transthoracic Needle Biopsy Increased the Risk of Pleural Recurrence in Pathological Stage I Lung Cancer Patients With Sub-pleural Pure Solid Nodules.

作者信息

Kashiwabara Kosuke, Semba Hiroshi, Fujii Shinji, Tsumura Shinsuke

机构信息

a Department of Respiratory Medicine , Kumamoto Regional Medical Center , Kumamoto , Japan.

出版信息

Cancer Invest. 2016 Sep 13;34(8):373-7. doi: 10.1080/07357907.2016.1212061. Epub 2016 Aug 17.

DOI:10.1080/07357907.2016.1212061
PMID:27532604
Abstract

We retrospectively evaluated whether preoperative percutaneous transthoracic needle biopsy (PTNB) affected the incidence of pleural recurrence in pathological stage I lung cancer patients. Pleural recurrence occurred in pure solid nodule (PSN) cases but not in ground-glass nodule cases, as evaluated using thin-section computed tomographic imaging. When the cases were restricted to sub-pleural PSN, the incidence of recurrence tended to be higher in a PTNB group (63 patients diagnosed by PTNB) than in a non-PTNB group (86 patients diagnosed by transbronchial biopsy or intraoperative diagnosis) (25% vs. 4%, p =.050). PTNB should not be performed in patients with a sub-pleural PSN.

摘要

我们进行了回顾性评估,以确定术前经皮经胸针吸活检(PTNB)是否会影响病理I期肺癌患者的胸膜复发率。根据薄层计算机断层扫描成像评估,胸膜复发发生在纯实性结节(PSN)病例中,而磨玻璃结节病例中未发生。当病例仅限于胸膜下PSN时,PTNB组(63例经PTNB诊断)的复发率往往高于非PTNB组(86例经支气管活检或术中诊断)(25%对4%,p = 0.050)。对于胸膜下PSN患者不应进行PTNB。

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