脉络膜黑色素瘤伴发的副肿瘤性卵黄样黄斑病变：一年的病程演变
PARANEOPLASTIC VITELLIFORM MACULOPATHY IN THE SETTING OF CHOROIDAL MELANOMA: EVOLUTION OVER ONE YEAR.
作者信息
Nagiel Aaron, Rootman Daniel B, McCannel Tara A
机构信息
*Retina Division, Stein Eye Institute, Los Angeles, California; †Orbital and Ophthalmic Plastic Surgery Division, Stein Eye Institute, Los Angeles, California; and ‡Doheny Eye Institute, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
出版信息
Retin Cases Brief Rep. 2017;11 Suppl 1:S7-S10. doi: 10.1097/ICB.0000000000000383.
BACKGROUND
To illustrate the evolution of paraneoplastic vitelliform maculopathy over one year using optical coherence tomography.
METHODS
Observational case report.
RESULTS
A 65-year-old man with a history of ocular melanocytosis and choroidal melanoma of the left eye treated with plaque brachytherapy 3 years prior returned for his yearly follow-up visit. The visual acuity in the right eye was 20/20. Subtle thickening of the interdigitation zone layer was noted on optical coherence tomography. Over the following year, multifocal vitelliform detachments developed with progressive enlargement and coalescence of the lesions. Paraneoplastic vitelliform maculopathy developed in the fellow eye of a patient with local recurrence of previously treated choroidal melanoma.
CONCLUSION
Paraneoplastic vitelliform maculopathy may develop in the fellow eye of a patient with local recurrence of their previously treated choroidal melanoma with no clinical evidence of systemic metastasis.
背景
使用光学相干断层扫描技术阐述副肿瘤性卵黄样黄斑病变在一年中的演变过程。
方法
观察性病例报告。
结果
一名65岁男性，有眼部黑素细胞增多症病史，左眼脉络膜黑色素瘤3年前接受了敷贴近距离放射治疗，前来进行年度随访。右眼视力为20/20。光学相干断层扫描显示指状交叉区层有细微增厚。在接下来的一年里，出现了多灶性卵黄样脱离，病变逐渐扩大并融合。副肿瘤性卵黄样黄斑病变发生在先前治疗的脉络膜黑色素瘤局部复发患者的对侧眼。
结论
先前治疗的脉络膜黑色素瘤局部复发且无全身转移临床证据的患者，其对侧眼可能发生副肿瘤性卵黄样黄斑病变。
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