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与多发性骨髓瘤相关的髋关节淀粉样关节病:一例报告

Amyloid Arthropathy of the Hip Joint Associated with Multiple Myeloma: A Case Report.

作者信息

Cho Yoon Je, Chun Young Soo, Rhyu Kee Hyung, Park Yong Koo, Ryu Kyung Nam, Park Ji Seon, Liang Huo, Jung Gwang Young, Shin Won Ju

机构信息

Department of Orthopedic Surgery, Kyung Hee University College of Medicine, Seoul, Korea.

Department of Orthopedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul, Korea.

出版信息

Hip Pelvis. 2016 Jun;28(2):127-31. doi: 10.5371/hp.2016.28.2.127. Epub 2016 Jun 30.

Abstract

Amyloidosis is a disease characterized by the deposition of non-soluble fibrous protein in multiple tissues with a number of possible causes. This protein deposition can occur in any tissue, yet is most commonly seen in kidneys, heart, and gastrointestinal tracts. However, invasion to bone tissues is not often reported. The deposition of amyloid proteins in bone tissues may result in joint pain and pathological fractures; it is important to elucidate the causes and detect early to determine prognosis and treat optimally. In the present case report, with relevant literature review, the authors report a case of total hip arthroplasty in an amyloidosis patient.

摘要

淀粉样变性是一种以不溶性纤维蛋白在多个组织中沉积为特征的疾病,其病因众多。这种蛋白质沉积可发生在任何组织中,但最常见于肾脏、心脏和胃肠道。然而,侵袭骨组织的情况并不常被报道。淀粉样蛋白在骨组织中的沉积可能导致关节疼痛和病理性骨折;阐明病因并早期检测对于确定预后和进行最佳治疗很重要。在本病例报告中,作者结合相关文献回顾,报道了一例淀粉样变性患者的全髋关节置换病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/096a/4972887/6e5492640736/hp-28-127-g001.jpg

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