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酵母杀伤毒素与双态性。

Yeast killer toxins and dimorphism.

作者信息

Polonelli L, Conti S, Campani L, Morace G, Fanti F

机构信息

Istituto di Microbiologia, Università degli Studi di Parma, Italy.

出版信息

J Clin Microbiol. 1989 Jun;27(6):1423-5. doi: 10.1128/jcm.27.6.1423-1425.1989.

DOI:10.1128/jcm.27.6.1423-1425.1989
PMID:2754015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267579/
Abstract

The differential action of four selected yeast killer toxins on the mycelial and yeast forms of four isolates of the dimorphic fungus Sporothrix schenckii was comparatively evaluated. The results confirmed that the yeast killer phenomenon is present among hyphomycetes and yeasts and that both morphological forms of S. schenckii are susceptible to the action of the same yeast killer toxin. Quantitative differences in the response to the killer action of the mycelial and yeast forms in individual strains were also observed. To avoid retroconversion of the dimorphic forms, we used a modification of the conventional killer system.

摘要

比较评估了四种选定的酵母杀伤毒素对双态真菌申克孢子丝菌四个分离株的菌丝体和酵母形式的差异作用。结果证实,酵母杀伤现象存在于丝孢菌和酵母中,并且申克孢子丝菌的两种形态形式均对相同的酵母杀伤毒素敏感。还观察到个别菌株的菌丝体和酵母形式对杀伤作用的反应存在定量差异。为避免双态形式的逆向转化,我们对传统的杀伤系统进行了改良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95e/267579/9e547b0bc34d/jcm00066-0300-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95e/267579/a6ee2ae7d41e/jcm00066-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95e/267579/9e547b0bc34d/jcm00066-0300-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95e/267579/a6ee2ae7d41e/jcm00066-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95e/267579/9e547b0bc34d/jcm00066-0300-b.jpg

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Yeast killer toxins and dimorphism.酵母杀伤毒素与双态性。
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引用本文的文献

1
Yeast killer systems.酵母杀伤系统
Clin Microbiol Rev. 1997 Jul;10(3):369-400. doi: 10.1128/CMR.10.3.369.
2
Genomic studies on killer yeasts belonging to the genus Pichia.
Antonie Van Leeuwenhoek. 1992 Oct;62(3):215-23. doi: 10.1007/BF00582582.

本文引用的文献

1
Effects of pH, temperature, aeration and carbon source on the development of the mycelial or yeast forms of Sporothrix schenckii from conidia.pH值、温度、通气和碳源对申克孢子丝菌分生孢子形成菌丝体或酵母形态的影响。
Mycopathologia. 1983 May 22;82(2):83-8. doi: 10.1007/BF00437335.
2
Killer system: a simple method for differentiating Candida albicans strains.杀伤系统:一种区分白色念珠菌菌株的简单方法。
J Clin Microbiol. 1983 May;17(5):774-80. doi: 10.1128/jcm.17.5.774-780.1983.
3
Molecular and cellular events during the yeast to mycelium transition in Sporothrix schenckii.
申克孢子丝菌从酵母态转变为菌丝态过程中的分子和细胞事件。
Sabouraudia. 1985 Jun;23(3):207-18. doi: 10.1080/00362178585380311.
4
Use of killer toxins for computer-aided differentiation of Candida albicans strains.利用杀伤毒素进行白色念珠菌菌株的计算机辅助鉴别
Mycopathologia. 1985 Sep;91(3):175-9. doi: 10.1007/BF00446297.
5
Reevaluation of the yeast killer phenomenon.
J Clin Microbiol. 1986 Nov;24(5):866-9. doi: 10.1128/jcm.24.5.866-869.1986.
6
Yeast killer toxin-like anti-idiotypic antibodies.酵母杀伤毒素样抗独特型抗体。
J Clin Microbiol. 1988 Mar;26(3):602-4. doi: 10.1128/jcm.26.3.602-604.1988.