马来西亚孕妇中的酵母菌感染与糖尿病
Yeast Infection and Diabetes Mellitus among Pregnant Mother in Malaysia.
作者信息
Sopian Iylia Liyana, Shahabudin Sa'adiah, Ahmed Mowaffaq Adam, Lung Leslie Than Thian, Sandai Doblin
机构信息
Infectomics Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Bertam, Penang, Malaysia.
Craniofacial and Biomaterials Sciences Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Bertam, Penang, Malaysia.
出版信息
Malays J Med Sci. 2016 Jan;23(1):27-34.
BACKGROUND
Vaginal yeast infection refers to irritation of the vagina due to the presence of opportunistic yeast of the genus Candida (mostly Candida albicans). About 75% of women will have at least one episode of vaginal yeast infection during their lifetime. Several studies have shown that pregnancy and uncontrolled diabetes increase the infection risk. Reproductive hormone fluctuations during pregnancy and elevated glucose levels characteristic of diabetes provide the carbon needed for Candida overgrowth and infection. The goal of this study was to determine the prevalence of vaginal yeast infection among pregnant women with and without diabetes.
METHODS
This was a case-control study using cases reports from Kepala Batas Health Clinic, Penang State, Malaysia from 2006 to 2012. In total, 740 pregnant ladies were chosen as sample of which 370 were diabetic and 370 were non-diabetic cases.
RESULTS
No relationship between diabetes and the occurrence of vaginal yeast infection in pregnant women was detected, and there was no significant association between infection and age group, race or education level.
CONCLUSION
In conclusion, within radius of this study, vaginal yeast infection can occur randomly in pregnant women.
背景
阴道酵母菌感染是指由于假丝酵母菌属（主要是白色念珠菌）这种机会性酵母菌的存在而引起的阴道刺激。约75%的女性在其一生中至少会经历一次阴道酵母菌感染。多项研究表明，怀孕和未控制的糖尿病会增加感染风险。怀孕期间的生殖激素波动以及糖尿病特有的血糖水平升高为念珠菌过度生长和感染提供了所需的碳源。本研究的目的是确定患有和未患有糖尿病的孕妇中阴道酵母菌感染的患病率。
方法
这是一项病例对照研究，使用了马来西亚槟城州北海健康诊所2006年至2012年的病例报告。总共选择了740名孕妇作为样本，其中370名是糖尿病患者，370名是非糖尿病患者。
结果
未检测到糖尿病与孕妇阴道酵母菌感染的发生之间存在关联，并且感染与年龄组、种族或教育水平之间也没有显著关联。
结论
总之，在本研究范围内，孕妇中阴道酵母菌感染可随机发生。
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