Division of Pulmonology, Department of Pediatrics, Thammasat University, Prathum Thani, Thailand.
Oral Biology Research Unit, Faculty of Dentistry, Thammasat University, Prathum Thani, Thailand.
Asian Pac J Allergy Immunol. 2017 Jun;35(2):102-107. doi: 10.12932/AP0753.
To evaluate the efficacy of positive-pressure nasal irrigation devices in children with acute sinusitis, in addition to bacterial colonization of the irrigation device.
We performed a randomized, prospective, controlled study of 80 children with acute sinusitis, aged between 3 and 15 years. Participants were randomly separated into two groups, where one group was treated using a squeezable bottle and the other group treated using a syringe. All patients were instructed to use a 1.25% buffered hypertonic solution for nasal irrigation twice daily for 2 weeks, in addition to amoxicillin-clavulanic acid. During this period, all participants recorded a 5S score, satisfaction score, any side effects and use of antihistamines. Parents were instructed to clean the device with soap after each use. After this period, the nasal irrigation devices were sent to a microbiological laboratory for bacterial identification.
At the 2-week follow-up, improvement in both 5S and satisfaction scores were observed in both groups compared to baseline, which were significantly higher in the group treated with the squeezable bottle compared to the syringe. Few complaints were reported, and side effects were equal in both groups. The overall rate of bacterial contamination for both treatments was approximately 80%, but this did not translate into higher rates of infection amongst patients.
The use of a squeezable bottle for nasal irrigation in children with acute sinusitis was associated with further improvements in 5S and satisfaction scores compared to syringe use, and there were no significant differences in bacterial contamination between methods.
评估正压鼻腔冲洗装置在急性鼻窦炎患儿中的疗效，以及该装置的细菌定植情况。
我们对 80 名年龄在 3 至 15 岁之间的急性鼻窦炎患儿进行了一项随机、前瞻性、对照研究。将参与者随机分为两组，一组使用挤压瓶治疗，另一组使用注射器治疗。所有患者均被指示使用 1.25%缓冲高渗溶液，每天进行两次鼻腔冲洗，持续 2 周，同时使用阿莫西林克拉维酸。在此期间，所有参与者记录了 5S 评分、满意度评分、任何副作用和抗组胺药物的使用情况。父母被指示在每次使用后用肥皂清洗设备。在此期间，将鼻腔冲洗设备送到微生物实验室进行细菌鉴定。
与基线相比，两组在 2 周随访时 5S 和满意度评分均有所改善，使用挤压瓶治疗的组明显高于使用注射器治疗的组。报告的投诉很少，两组的副作用相等。两种治疗方法的总体细菌污染率约为 80%，但这并未导致患者感染率的升高。
与使用注射器相比，在急性鼻窦炎患儿中使用挤压瓶进行鼻腔冲洗与 5S 和满意度评分的进一步改善相关，两种方法之间的细菌污染没有显著差异。
