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使用分层贝叶斯模型估计评估纽约市大都市区细颗粒物(PM)对呼吸-心血管慢性疾病的影响。

Assessing the impact of fine particulate matter (PM) on respiratory-cardiovascular chronic diseases in the New York City Metropolitan area using Hierarchical Bayesian Model estimates.

作者信息

Weber Stephanie A, Insaf Tabassum Z, Hall Eric S, Talbot Thomas O, Huff Amy K

机构信息

Battelle Memorial Institute, Columbus, OH, United States.

New York State Department of Health, Albany, NY, United States; School of Public Health, University at Albany, SUNY, Rensselaer, NY, United States.

出版信息

Environ Res. 2016 Nov;151:399-409. doi: 10.1016/j.envres.2016.07.012. Epub 2016 Aug 17.

DOI:10.1016/j.envres.2016.07.012
PMID:27543787
Abstract

An enhanced research paradigm is presented to address the spatial and temporal gaps in fine particulate matter (PM) measurements and generate realistic and representative concentration fields for use in epidemiological studies of human exposure to ambient air particulate concentrations. The general approach for research designed to analyze health impacts of exposure to PM is to use concentration data from the nearest ground-based air quality monitor(s), which typically have missing data on the temporal and spatial scales due to filter sampling schedules and monitor placement, respectively. To circumvent these data gaps, this research project uses a Hierarchical Bayesian Model (HBM) to generate estimates of PM in areas with and without air quality monitors by combining PM concentrations measured by monitors, PM concentration estimates derived from satellite aerosol optical depth (AOD) data, and Community-Multiscale Air Quality (CMAQ) model predictions of PM concentrations. This methodology represents a substantial step forward in the approach for developing representative PM concentration datasets to correlate with inpatient hospitalizations and emergency room visits data for asthma and inpatient hospitalizations for myocardial infarction (MI) and heart failure (HF) using case-crossover analysis. There were two key objective of this current study. First was to show that the inputs to the HBM could be expanded to include AOD data in addition to data from PM monitors and predictions from CMAQ. The second objective was to determine if inclusion of AOD surfaces in HBM model algorithms results in PM air pollutant concentration surfaces which more accurately predict hospital admittance and emergency room visits for MI, asthma, and HF. This study focuses on the New York City, NY metropolitan and surrounding areas during the 2004-2006 time period, in order to compare the health outcome impacts with those from previous studies and focus on any benefits derived from the changes in the HBM model surfaces. Consistent with previous studies, the results show high PM exposure is associated with increased risk of asthma, myocardial infarction and heart failure. The estimates derived from concentration surfaces that incorporate AOD had a similar model fit and estimate of risk as compared to those derived from combining monitor and CMAQ data alone. Thus, this study demonstrates that estimates of PM concentrations from satellite data can be used to supplement PM monitor data in the estimates of risk associated with three common health outcomes. Results from this study were inconclusive regarding the potential benefits derived from adding AOD data to the HBM, as the addition of the satellite data did not significantly increase model performance. However, this study was limited to one metropolitan area over a short two-year time period. The use of next-generation, high temporal and spatial resolution satellite AOD data from geostationary and polar-orbiting satellites is expected to improve predictions in epidemiological studies in areas with fewer pollutant monitors or over wider geographic areas.

摘要

本文提出了一种改进的研究范式,以解决细颗粒物(PM)测量中的时空差距,并生成现实且具有代表性的浓度场,用于人类暴露于环境空气颗粒物浓度的流行病学研究。旨在分析暴露于PM对健康影响的一般研究方法是使用来自最近的地面空气质量监测器的浓度数据,由于过滤器采样计划和监测器位置的原因,这些数据在时间和空间尺度上通常存在缺失数据。为了规避这些数据差距,本研究项目使用分层贝叶斯模型(HBM),通过结合监测器测量的PM浓度、从卫星气溶胶光学深度(AOD)数据得出的PM浓度估计值以及社区多尺度空气质量(CMAQ)模型对PM浓度的预测,来生成有无空气质量监测器区域的PM估计值。这种方法在开发代表性PM浓度数据集的方法上向前迈出了重要一步,该数据集可通过病例交叉分析与哮喘住院和急诊就诊数据以及心肌梗死(MI)和心力衰竭(HF)住院数据相关联。本研究有两个关键目标。第一个目标是表明HBM的输入可以扩展到除了PM监测器数据和CMAQ预测之外还包括AOD数据。第二个目标是确定在HBM模型算法中纳入AOD表面是否会导致PM空气污染物浓度表面更准确地预测MI、哮喘和HF的住院率和急诊就诊率。本研究聚焦于2004 - 2006年期间纽约市、纽约大都市及周边地区,以便将健康结果影响与先前研究的结果进行比较,并关注HBM模型表面变化带来的任何益处。与先前研究一致,结果表明高PM暴露与哮喘、心肌梗死和心力衰竭风险增加相关。与仅结合监测器和CMAQ数据得出的浓度表面相比,纳入AOD的浓度表面得出的估计值具有相似的模型拟合度和风险估计。因此,本研究表明,在与三种常见健康结果相关的风险估计中,卫星数据得出的PM浓度估计值可用于补充PM监测器数据。关于将AOD数据添加到HBM中可能带来的益处,本研究结果尚无定论,因为添加卫星数据并未显著提高模型性能。然而,本研究仅限于一个大都市地区,时间跨度较短,仅两年。预计使用来自地球静止卫星和极轨卫星的下一代高时空分辨率卫星AOD数据将改善污染物监测器较少地区或更广泛地理区域的流行病学研究预测。

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