Lin Kun-de, Chen Yan-qiu, Yuan Dong-xing
Huan Jing Ke Xue. 2016 Apr 15;37(4):1576-83.
Polyhalogenated carbazoles (PHCs), with a complex chemical structure similar to polychlorinated dibenzofurans, are a class of emerging environmental organic contaminants. There are 135 congeners for PHCs with a pure halogenation. Most of PHCs are not man-made products. Although PHCs in the environment were firstly discovered in the 1980s, these emerging halogenated compounds were not seriously considered until recent years. Recently, more than 20 PHCs have been detected in sediment and soil samples. In addition, studies have shown that PHCs exhibited dioxin-like toxicity and were persistent and bioaccumulative. Therefore, it is very important to understand the distribution, origins and ecotoxicology of PHCs for a better assessment of their environmental risks. To date, research on the environmental behaviors of PHCs is relatively limited and warrants further investigations. In this review, the environmental distribution, source, analytical methods and toxicity of PHCs were summarized and future research needs were outlined.
多卤代咔唑(PHCs)的化学结构复杂,与多氯二苯并呋喃相似,是一类新出现的环境有机污染物。PHCs有135种纯卤代的同系物。大多数PHCs并非人造产品。尽管环境中的PHCs在20世纪80年代首次被发现,但这些新出现的卤代化合物直到近年来才受到认真关注。最近,在沉积物和土壤样本中检测到了20多种PHCs。此外,研究表明,PHCs具有二噁英样毒性,且具有持久性和生物累积性。因此,了解PHCs的分布、来源和生态毒理学对于更好地评估其环境风险非常重要。迄今为止,关于PHCs环境行为的研究相对有限,值得进一步研究。在这篇综述中,总结了PHCs的环境分布、来源、分析方法和毒性,并概述了未来的研究需求。