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到2017年,欧盟范围内因胰腺癌死亡的人数超过了因乳腺癌死亡的人数。

More deaths from pancreatic cancer than breast cancer in the EU by 2017.

作者信息

Ferlay J, Partensky C, Bray F

机构信息

a Section of Cancer Surveillance , International Agency for Research on Cancer , Lyon , France.

b Section of Infections and Cancer Epidemiology , International Agency for Research on Cancer , Lyon , France.

出版信息

Acta Oncol. 2016 Sep-Oct;55(9-10):1158-1160. doi: 10.1080/0284186X.2016.1197419. Epub 2016 Aug 23.

Abstract

INTRODUCTION

Pancreatic cancer currently ranks below female breast cancer in terms of the number of deaths in both males and females in the EU. While breast cancer mortality rates have been declining in many higher income EU countries during recent decades, rates of pancreatic cancer in contrast are either stable or moderately increasing; a comparative analysis of the short-term future rates of both is warranted.

METHODS

We extracted the annual number of deaths from cancers of the pancreas and breast by gender together with population at risk in each of 28 countries of the EU for the period 2001-2010. We fitted cancer- and gender-specific time-linear regression models and predicted deaths from pancreatic and breast cancer mortality for the years 2011-2025.

RESULTS

We estimated that by the year 2017 more deaths from pancreatic cancer will occur (91 500 annual deaths) than breast cancer (91 000) in the EU. By 2025, deaths from cancer of the pancreas are predicted to be 25% higher (111 500 and 90 000, respectively). Pancreatic cancer may become the third leading cause of death from cancer in the EU after lung and colorectal cancers.

CONCLUSION

Although strategies may emerge in the near future that will enhance the prospects of improving the very poor five-year survival from pancreatic cancer, coordinated efforts are necessary to reduce the foreseeable high mortality burden of disease within the EU.

摘要

引言

在欧盟,目前胰腺癌导致的男性和女性死亡人数均低于女性乳腺癌。近几十年来,许多高收入欧盟国家的乳腺癌死亡率一直在下降,而胰腺癌的死亡率则要么稳定,要么适度上升;因此有必要对两者的短期未来死亡率进行比较分析。

方法

我们提取了2001年至2010年期间欧盟28个国家中按性别划分的胰腺癌和乳腺癌年度死亡人数以及各年度的危险人群数量。我们拟合了特定癌症和性别的时间线性回归模型,并预测了2011年至2025年胰腺癌和乳腺癌的死亡人数。

结果

我们估计,到2017年,欧盟因胰腺癌死亡的人数(每年91500人)将超过因乳腺癌死亡的人数(91000人)。到2025年,预计胰腺癌死亡人数将高出25%(分别为111500人和90000人)。胰腺癌可能成为欧盟继肺癌和结直肠癌之后的第三大癌症死因。

结论

尽管在不久的将来可能会出现一些策略来改善胰腺癌极低的五年生存率,但仍需要协调各方努力,以减轻欧盟内可预见的高疾病死亡负担。

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