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CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
Cell Metab. 2016 Jun 14;23(6):1127-1139. doi: 10.1016/j.cmet.2016.05.006.
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Sirtuin functions and modulation: from chemistry to the clinic.
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SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Cell. 2016 Jun 2;165(6):1401-1415. doi: 10.1016/j.cell.2016.04.033. Epub 2016 May 12.
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NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126/science.aaf2693. Epub 2016 Apr 28.
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A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis.
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Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart.
Cell Rep. 2015 Oct 20;13(3):533-545. doi: 10.1016/j.celrep.2015.09.023. Epub 2015 Oct 8.
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The multifaceted functions of sirtuins in cancer.
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A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease.
Neurology. 2015 Oct 20;85(16):1383-91. doi: 10.1212/WNL.0000000000002035. Epub 2015 Sep 11.
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Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.
Nat Med. 2015 Aug;21(8):887-94. doi: 10.1038/nm.3882. Epub 2015 Jul 13.
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Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Nat Commun. 2015 Jul 2;6:7645. doi: 10.1038/ncomms8645.
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