Zenebe Tizazu, Tefera Ermias
Debre Berhan University, Debre Berhan, Ethiopia.
Afar Regional Health Bureau, Afar, Ethiopia.
Braz J Infect Dis. 2016 Nov-Dec;20(6):635-636. doi: 10.1016/j.bjid.2016.07.012. Epub 2016 Aug 21.
Evaluating the outcomes of tuberculosis treatment and understanding the specific reasons for unfavorable treatment outcome are important in evaluating the effectiveness of tuberculosis control program. A retrospective study was conducted to assess tuberculosis treatment outcomes and associated factors among smear positive pulmonary tuberculosis patients in zone-one health facilities of Afar regional state, Ethiopia. A total of 380 smear positive pulmonary tuberculosis patients' registration book recorded with complete information from Jan 2011 to Dec 2013 were analyzed. Of 380 patients included in the analysis, 238 were male and 142 female with mean age of 30.7. Overall treatment outcome were 128 (33.7%) cured, 192 (50.2%) completed, 17 (4.5%) died, 1 (0.3%) treatment failure, 34 (8.9%) default and 8 (2.1%) transfer out. Treatment success rate was 81.8%. There was statistically significance association between age (p-value=0.000), sex (p-value=0.018), HIV status (p-value=0.000), four week attendance (p-value=0.000), sputum follow up test (p-value=0.000), and treatment outcome year (p-value=0.000), and treatment success (p-value=0.000). Treatment success rate almost reached to the WHO targets although yet need to work a lot for fulfillment of global targets. Regular four week attendance in continuation phase and doing follow up sputum test with unsuccessful outcome for smear positive tuberculosis patient were vital.
评估结核病治疗结果并了解治疗结果不佳的具体原因对于评估结核病控制项目的有效性至关重要。在埃塞俄比亚阿法尔州第一区卫生设施中,开展了一项回顾性研究,以评估涂片阳性肺结核患者的结核病治疗结果及相关因素。分析了2011年1月至2013年12月期间记录的380例信息完整的涂片阳性肺结核患者登记册。分析纳入的380例患者中,男性238例,女性142例,平均年龄30.7岁。总体治疗结果为:治愈128例(33.7%),完成治疗192例(50.2%),死亡17例(4.5%),治疗失败1例(0.3%),中断治疗34例(8.9%),转出8例(2.1%)。治疗成功率为81.8%。年龄(p值 = 0.000)、性别(p值 = 0.018)、艾滋病毒感染状况(p值 = 0.000)、四周就诊情况(p值 = 0.000)、痰涂片随访检测(p值 = 0.000)以及治疗结果年份(p值 = 0.000)与治疗成功(p值 = 0.000)之间存在统计学显著关联。尽管要实现全球目标仍需付出很多努力,但治疗成功率几乎达到了世界卫生组织的目标。对于涂片阳性肺结核患者,在继续治疗阶段定期四周就诊并进行痰涂片随访检测且结果不理想至关重要。