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Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2.

作者信息

Orgel Kelly A, Duan Shiteng, Wright Benjamin L, Maleki Soheila J, Wolf John C, Vickery Brian P, Burks A Wesley, Paulson James C, Kulis Mike D, Macauley Matthew S

机构信息

Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC; UNC Food Allergy Initiative, Chapel Hill, NC; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC.

Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, Calif; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, Calif; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, Calif.

出版信息

J Allergy Clin Immunol. 2017 Jan;139(1):366-369.e2. doi: 10.1016/j.jaci.2016.06.053. Epub 2016 Aug 20.

Abstract
摘要

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本文引用的文献

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Suppression of the immunologic response to peanut during immunotherapy is often transient.
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3
Siglec-mediated regulation of immune cell function in disease.
Nat Rev Immunol. 2014 Oct;14(10):653-66. doi: 10.1038/nri3737. Epub 2014 Sep 19.
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State of the art on food allergen immunotherapy: oral, sublingual, and epicutaneous.
J Allergy Clin Immunol. 2014 Feb;133(2):318-23. doi: 10.1016/j.jaci.2013.12.1040.
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Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis.
J Clin Invest. 2013 Jul;123(7):3074-83. doi: 10.1172/JCI69187. Epub 2013 Jun 3.
7
IgE cross-reactivity between the major peanut allergen Ara h 2 and the nonhomologous allergens Ara h 1 and Ara h 3.
J Allergy Clin Immunol. 2013 Jul;132(1):118-24. doi: 10.1016/j.jaci.2013.01.022. Epub 2013 Mar 5.

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