Sen Chandan K, Ghatak Subhadip, Gnyawali Surya C, Roy Sashwati, Gordillo Gayle M
Columbus, Ohio.
From the Center for Regenerative Medicine & Cell-Based Therapies, Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center.
Plast Reconstr Surg. 2016 Sep;138(3 Suppl):119S-128S. doi: 10.1097/PRS.0000000000002654.
Wound assessment relies on visual evaluation by physicians. Such assessment is largely subjective and presents the opportunity to explore the use of emergent technologies.
Emergent and powerful noninvasive imaging technologies applicable to assess burn and chronic wounds are reviewed.
The need to estimate wound depth is critical in both chronic wound and burn injury settings. Harmonic ultrasound technology is powerful to study wound depth. It addresses the limitations of optical imaging with limited depth of penetration. What if a wound appears epithelialized by visual inspection, which shows no discharge yet is covered by repaired skin that lacks barrier function? In this case although the wound is closed as defined by current standards, it remains functionally open, presenting the risk of infection and other postclosure complications. Thus, assessment of skin barrier function is valuable in the context of assessing wound closure. Options for the study of tissue vascularization are many. If noncontact and noninvasive criteria are of importance, laser speckle imaging is powerful. Fluorescence imaging is standard in several clinical settings and is likely to serve the wound clinics well as long as indocyanine green injection is not of concern. A major advantage of harmonic ultrasound imaging of wound depth is that the same system is capable of providing information on blood flow dynamics in arterial perforators.
With many productive imaging platforms to choose from, wound care is about to be transformed by technology that would help assess wound severity.
伤口评估依赖于医生的视觉评估。这种评估在很大程度上是主观的,为探索新兴技术的应用提供了契机。
对适用于评估烧伤和慢性伤口的新兴且强大的非侵入性成像技术进行综述。
在慢性伤口和烧伤创面情况下,估计伤口深度的需求至关重要。谐波超声技术在研究伤口深度方面很强大。它克服了光学成像穿透深度有限的局限性。如果一个伤口通过肉眼检查看起来已上皮化,没有渗出物,但被缺乏屏障功能的修复皮肤覆盖,会怎样呢?在这种情况下,尽管按照当前标准伤口已闭合,但在功能上它仍然是开放的,存在感染和其他闭合后并发症的风险。因此,在评估伤口闭合的背景下,评估皮肤屏障功能很有价值。研究组织血管化的方法有很多。如果非接触和非侵入性标准很重要,激光散斑成像很强大。荧光成像在一些临床环境中是标准方法,只要不考虑注射吲哚菁绿,它很可能在伤口诊所发挥很好的作用。谐波超声成像评估伤口深度的一个主要优点是同一系统能够提供有关动脉穿支血流动力学的信息。
有许多有效的成像平台可供选择,伤口护理即将因有助于评估伤口严重程度的技术而发生变革。