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[高氧对白蛋白替代大量失血大鼠全身血流动力学、微循环及氧疗的影响]

[Effect of hyperoxia on systemic hemodynamics, microcirculation, and oxygen regimen in rats in replacement of massive blood loss by albumin].

作者信息

Kochetygov N I, Dolgushina A D, Gorkun A V

出版信息

Patol Fiziol Eksp Ter. 1989 Mar-Apr(2):35-9.

PMID:2755722
Abstract

Experiments were conducted on rats to study systemic hemodynamics, microcirculation, and oxygen regimen in the organism in replacement of massive blood loss with albumin solution in normo- and hyperoxia. The results suggest that in breathing oxygen conditions are created in the organism for fuller realization of the mechanism of compensatory increase of the minute circulation volume in replacement of blood loss by a blood substitute, as a result of which total oxygen consumption increases and microcirculation is restored more adequately.

摘要

在大鼠身上进行了实验,以研究在常氧和高氧条件下用白蛋白溶液替代大量失血时,机体的全身血流动力学、微循环和氧代谢情况。结果表明,在吸氧条件下,机体能够创造出有利于更充分实现用血液替代品替代失血时每分钟循环血量代偿性增加机制的条件,从而使总氧耗增加,微循环得到更充分恢复。

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