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小脑脑桥角区罕见的淋巴浆细胞淋巴瘤病例报告并文献复习

An uncommon case of lymphoplasmacytic lymphoma in cerebellopontine angle region: Case report with a literature review.

作者信息

Yan Chengrui, Kong Xiangyi, Yang Lanshu, Ma Wenbin

机构信息

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing, P. R. China.

出版信息

Medicine (Baltimore). 2016 Aug;95(34):e4627. doi: 10.1097/MD.0000000000004627.

Abstract

In the central nervous system, cerebellopontine angle (CPA) lymphomas are rare; few cases have been reported. Lymphoplasmacytic lymphoma (LPL) in the CPA is rarer still, and often misdiagnosed as acoustic neuroma.We report a rare case of CPA LPL-a challenging diagnosis guided by clinical presentations, radiological signs, and postoperative pathological test.A 43-year-old woman presented with headaches. Her magnetic resonance imaging revealed an abnormal homogeneously enhancing mass in the left CPA. We present detailed analysis of her disease and review relevant literature.When surgically treated, her specimen showed a typical LPL histopathology pattern. After surgery, the patient's symptoms improved greatly, and she received chemotherapy.Despite its rarity, LPL should be considered in differential diagnoses of CPA lesions that mimic acoustic neuromas.

摘要

在中枢神经系统中,小脑脑桥角(CPA)淋巴瘤较为罕见,仅有少数病例报道。CPA区域的淋巴浆细胞淋巴瘤(LPL)更为罕见,且常被误诊为听神经瘤。我们报告了一例罕见的CPA LPL病例——这是一例通过临床表现、影像学征象及术后病理检查进行挑战性诊断的病例。一名43岁女性因头痛就诊。其磁共振成像显示左侧CPA有一个异常的均匀强化肿块。我们对她的病情进行了详细分析并复习了相关文献。手术治疗时,她的标本显示出典型的LPL组织病理学模式。术后,患者症状大幅改善,并接受了化疗。尽管LPL罕见,但在鉴别诊断类似听神经瘤的CPA病变时应考虑到该病。

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