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A型主动脉夹层何时以及如何进行主动脉根部置换。

When and how to replace the aortic root in type A aortic dissection.

作者信息

Leshnower Bradley G, Chen Edward P

机构信息

Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Ann Cardiothorac Surg. 2016 Jul;5(4):377-82. doi: 10.21037/acs.2016.03.15.

Abstract

Management of aortic root pathology during repair of acute type A aortic dissection (TAAD) requires a comprehensive evaluation of the patient's anatomy, demographics, comorbidities and physiologic status at the time of emergent operative intervention. Surgical options include conservative repair of the root (CRR) (with or without replacement of the aortic valve), replacement of the native valve and aortic root using a composite valve-conduit and valve sparing root replacement (VSRR). The primary objective of this review is to provide data for surgeons to aid in their decision-making process regarding management of the aortic root during repair of TAAD. No time or language restrictions were imposed and references of the selected studies were checked for additional relevant citations. Multiple retrospective reviews have demonstrated equivalent operative mortality between aortic root repair and replacement during TAAD. There is a higher incidence of aortic root reintervention with aortic root repair compared to aortic root replacement (ARR). Experienced, high-volume aortic centers have demonstrated the safety of VSRR in young, hemodynamically stable patients presenting with TAAD. In conclusion, aortic root repair can safely be performed in the vast majority of patients with TAAD. Despite the increased surgical complexity, ARR does not increase operative mortality and improves the freedom from root reintervention. VSRR can be performed in highly selected populations of patients with TAAD with durable mid-term valve function.

摘要

急性A型主动脉夹层(TAAD)修复术中主动脉根部病变的处理需要在紧急手术干预时对患者的解剖结构、人口统计学特征、合并症和生理状态进行全面评估。手术选择包括主动脉根部保守修复(CRR)(伴或不伴主动脉瓣置换)、使用复合瓣膜管道置换自体瓣膜和主动脉根部以及保留瓣膜的根部置换(VSRR)。本综述的主要目的是为外科医生提供数据,以帮助他们在TAAD修复术中就主动脉根部的处理做出决策。本研究没有设置时间或语言限制,并对所选研究的参考文献进行了检查以获取更多相关引用。多项回顾性研究表明,TAAD期间主动脉根部修复和置换的手术死亡率相当。与主动脉根部置换(ARR)相比,主动脉根部修复术后主动脉根部再次干预的发生率更高。经验丰富、手术量大的主动脉中心已证明VSRR在年轻、血流动力学稳定的TAAD患者中的安全性。总之,绝大多数TAAD患者都可以安全地进行主动脉根部修复。尽管手术复杂性增加,但ARR并不会增加手术死亡率,且能提高避免根部再次干预的自由度。VSRR可在经过严格筛选的TAAD患者群体中进行,中期瓣膜功能持久。

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