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急性A型主动脉夹层的根部处理:我们是否准备好采用标准化方法?

Managing the Root in Acute Type A Aortic Dissections: Are We Ready for a Standardized Approach?

作者信息

Lopez-Marco Ana, Yates Martin T, Adams Benjamin, Lall Kulvinder, Yap John, Di Salvo Carmelo, Uppal Rakesh, Oo Aung

机构信息

Department of Cardiothoracic Surgery, St. Bartholomew's Hospital, London, United Kingdom.

出版信息

Aorta (Stamford). 2023 Feb;11(1):1-9. doi: 10.1055/s-0042-1757947. Epub 2023 Feb 27.

Abstract

OBJECTIVES

Surgical repair of Type A aortic dissection (TAAD) requires exclusion of the primary entry tear and reestablishment of flow into the distal true lumen. Provided that the majority of tears occur within the ascending aorta (AA), replacing only that segment seems a safe option; however, this strategy leaves the root susceptible to dilatation and need for reintervention. We aimed to review the outcomes of the two strategies: aortic root replacement (ARR) and isolated ascending aortic replacement.

METHODS

Retrospective analysis of prospectively collected data for all consecutive patients who underwent repair of acute TAAD at our institution from 2015 to 2020 was conducted. Patients were divided into two groups: (1) ARR and (2) isolated AA replacement as index operation for TAAD repair. Primary outcomes were mortality and need for reintervention during the follow-up.

RESULTS

A total of 194 patients were included in the study; 68 (35%) in the ARR group and 126 (65%) in the AA group. There were no significant differences in postoperative complications or in-hospital mortality (23%;  = 0.51) between groups. Seven patients (4.7%) died during follow-up and eight patients underwent aortic reinterventions, including proximal aortic segments (two patients) and distal procedures (six patients).

CONCLUSION

Both aortic root and AA replacement are acceptable and safe techniques. The growth of an untouched root is slow, and reintervention in this aortic segment is infrequent compared with distal aortic segments, hence preserving the root could be an option for older patients provided that there is no primary tear within the root.

摘要

目的

A型主动脉夹层(TAAD)的外科修复需要封闭原发破口并重建远端真腔血流。鉴于大多数破口发生在升主动脉(AA)内,仅替换该节段似乎是一种安全的选择;然而,这种策略会使主动脉根部易发生扩张并需要再次干预。我们旨在回顾两种策略的结果:主动脉根部置换(ARR)和单纯升主动脉置换。

方法

对2015年至2020年在我们机构接受急性TAAD修复的所有连续患者的前瞻性收集数据进行回顾性分析。患者分为两组:(1)ARR组和(2)单纯AA置换组,作为TAAD修复的索引手术。主要结局是随访期间的死亡率和再次干预的需求。

结果

本研究共纳入194例患者;ARR组68例(35%),AA组126例(65%)。两组术后并发症或住院死亡率(23%;P = 0.51)无显著差异。7例患者(4.7%)在随访期间死亡,8例患者接受了主动脉再次干预,包括近端主动脉节段(2例患者)和远端手术(6例患者)。

结论

主动脉根部置换和AA置换都是可接受且安全的技术。未触及的根部生长缓慢,与远端主动脉节段相比,该主动脉节段的再次干预较少,因此对于老年患者,如果根部没有原发破口,保留根部可能是一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9bb/9970750/07c4aa2b95d7/10-1055-s-0042-1757947-i210038-1.jpg

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