Vendramin Igor, Piani Daniela, Lechiancole Andrea, Sponga Sandro, Muser Daniele, Imazio Massimo, Onorati Francesco, Auci Elisabetta, Bortolotti Uberto, Livi Ugolino
Azienda Sanitaria Universitaria Friuli Centrale, Cardiothoracic Department, Via Pozzuolo 11, 33100 Udine, Italy.
Azienda Ospedaliero-Universitaria di Verona, Cardiothoracic and Vascular Department, 37126 Verona, Italy.
Rev Cardiovasc Med. 2022 Jun 24;23(7):228. doi: 10.31083/j.rcm2307228. eCollection 2022 Jul.
In patients with acute type A aortic dissection (A-AAD) whether initial repair should include also aortic arch replacement is still debated. We aimed to assess if extensive aortic repair prevents from reoperations patients with A-AAD.
Outcomes after distal reoperation following repair of A-AAD (n = 285; 1977 to 2018) were analysed in 22 of 226 who underwent ascending aorta/hemiarch replacement (Group ) and 7 of 59 who had ascending aorta/arch replacement (Group ).
Distal reoperation was more common in Group (n = 22) than in Group (n = 0) ( 0.001) while thoracic endovascular stenting was more frequent in Group (7 vs 3, 0.001). Indications for reoperation were pseudoaneurysm at distal anastomosis (n = 4, 18%) and progression of aortic dissection (n = 18, 82%) in Group . Indication for thoracic endovascular stenting was progressive aortic dissection in 3 patients of Group and in 6 of Group . Second reoperation was required in 2 patients from Group (2%) during a mean follow-up of 5 years. Median follow-up was 4 years in Group and 7 years in Group ( = 0.36). Hospital mortality was 14% in Group and 0% in Group ( = 0.3). Actuarial survival is 68 10%, and 62 11% for Group and 100% for Group at 5 and 10 years ( = 0.076).
Distal reoperations after A-AAD repair have an acceptable mortality. An extensive initial repair has lower rate of reoperation and better mid-term survival and should be indicated especially for young patients in experienced centers.
对于急性A型主动脉夹层(A - AAD)患者,初始修复是否应包括主动脉弓置换仍存在争议。我们旨在评估广泛的主动脉修复能否预防A - AAD患者再次手术。
分析了226例接受升主动脉/半弓置换的患者中的22例(A组)和59例接受升主动脉/全弓置换的患者中的7例(B组)在A - AAD修复后进行远端再次手术的结果(n = 285;1977年至2018年)。
A组(n = 22)远端再次手术比B组(n = 0)更常见(P < 0.001),而B组胸主动脉腔内支架置入术更频繁(7例对3例,P < 0.001)。A组再次手术的指征为远端吻合口假性动脉瘤(n = 4,18%)和主动脉夹层进展(n = 18,82%)。胸主动脉腔内支架置入术的指征在B组3例患者和A组6例患者中为主动脉夹层进展。A组2例患者(2%)在平均5年的随访期间需要二次再次手术。A组中位随访时间为4年,B组为7年(P = 0.36)。A组医院死亡率为14%,B组为0%(P = 0.3)。5年和10年时,A组的精算生存率分别为68% ± 10%,B组为62% ± 11%,B组为100%(P = 0.076)。
A - AAD修复术后远端再次手术死亡率可接受。广泛的初始修复再次手术率较低,中期生存率更好,尤其对于经验丰富中心的年轻患者应予以推荐。