Agarwal Shivam, Jaiswal Vijay, Singh Dharamveer, Jaiswal Prateek, Garg Amit, Upadhyay Amit
Department of Pediatrics, LLRM Medical College, Meerut, UP, India.
Department of Pediatrics, PGIMER Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Acta Paediatr. 2016 Nov;105(11):e526-e530. doi: 10.1111/apa.13559.
Placental redistribution has been shown to improve haematological outcomes in the immediate neonatal period and early infancy. This study compared the effects of delayed cord clamping (DCC) and umbilical cord milking (UCM) on haematological and growth parameters at 12 months of age.
This was a follow-up study of a randomised control trial, conducted in a tertiary care paediatric centre from August 2013 to August 2014. We studied 200 apparently healthy Indian infants randomised at birth to receive DCC for 60-90 seconds or UCM. The outcome measures were iron status and physical growth parameters at 12 months.
Of the 200 babies, 161 completed the follow-up and baseline characteristics were comparable in both groups. The mean haemoglobin in the DCC group (102.2 (17.2) g/L and serum ferritin 16.44 (2.77) μg/L) showed no significant differences to the UCM group (98.6 (17.1) g/L and 18.2 (2.8) μg/L) at one year. In addition, there were no significant differences in weight, height and mid-upper arm circumference in the two groups.
Term-born Indian infants who had DCC at 60-90 seconds or UCM showed no significant differences in ferritin and haemoglobin levels and growth parameters at 12 months of age.
胎盘再分布已被证明可改善新生儿早期和婴儿期的血液学指标。本研究比较了延迟脐带结扎(DCC)和脐带挤血(UCM)对12月龄时血液学和生长参数的影响。
这是一项对随机对照试验的随访研究,于2013年8月至2014年8月在一家三级儿科护理中心进行。我们研究了200名出生时随机分组的表面健康的印度婴儿,一组接受60 - 90秒的DCC,另一组接受UCM。观察指标为12月龄时的铁状态和身体生长参数。
200名婴儿中,161名完成了随访,两组的基线特征具有可比性。1岁时,DCC组的平均血红蛋白(102.2(17.2)g/L)和血清铁蛋白(16.44(2.77)μg/L)与UCM组(98.6(17.1)g/L和18.2(2.8)μg/L)相比,无显著差异。此外,两组在体重、身高和上臂中部周长方面也无显著差异。
出生时接受60 - 90秒DCC或UCM的足月儿在12月龄时,铁蛋白、血红蛋白水平和生长参数无显著差异。