中国产气肠杆菌中新型德里金属β-内酰胺酶（由bla编码）的检测
Detection of New Delhi Metallo-Beta-Lactamase (Encoded by bla ) in Enterobacter aerogenes in China.
作者信息
Shen Yong, Xiao Wei-Qiang, Gong Jiao-Mei, Pan Jun, Xu Qing-Xia
机构信息
Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China.
Department of Clinical Laboratory, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
出版信息
J Clin Lab Anal. 2017 Mar;31(2). doi: 10.1002/jcla.22044. Epub 2016 Aug 27.
Abstract
BACKGROUND
The increase in bla in Enterobacteriaceae has become a major concern worldwide. In previous study, we investigated clonal dissemination and mechanisms of resistance to carbapenem in China.
METHODS
We carried out retrospective surveillance for bla among carbapenem-resistant enterobacter strains, which were isolated from patients at our hospital by bacterial strains selection, antimicrobial susceptibility testing, species identification, and molecular detection of resistance gene.
RESULTS
We found three bla -positive isolates which were identified as Enterobacter aerogenes in clinical patients in China. The bla -positive Enterobacter aerogenes isolates were first found.
CONCLUSION
It is important to mandate prudent usage of antibiotics and implement infection control measures to control the spread of these resistant bla -positive strains.
摘要
背景
肠杆菌科细菌中bla的增加已成为全球主要关注的问题。在先前的研究中，我们调查了中国碳青霉烯耐药肠杆菌的克隆传播及耐药机制。
方法
我们对耐碳青霉烯肠杆菌菌株中的bla进行了回顾性监测，这些菌株是通过细菌菌株筛选、抗菌药物敏感性测试、菌种鉴定以及耐药基因的分子检测从我院患者中分离出来的。
结果
我们在中国临床患者中发现了三株bla阳性分离株，它们被鉴定为产气肠杆菌。首次发现了bla阳性产气肠杆菌分离株。
结论
强制谨慎使用抗生素并实施感染控制措施对于控制这些耐药bla阳性菌株的传播很重要。
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