染色质纤维：从经典描述到现代解读
Chromatin fibers: from classical descriptions to modern interpretation.
作者信息
Kuznetsova Maria A, Sheval Eugene V
机构信息
Faculty of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, 119992, Moscow, Russia.
A.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119992, Moscow, Russia.
出版信息
Cell Biol Int. 2016 Nov;40(11):1140-1151. doi: 10.1002/cbin.10672. Epub 2016 Sep 20.
The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that time, a plethora of fibrillar substructures have been described inside the mitotic chromosomes, and published data indicate that chromosomes may be formed as a result of the hierarchical folding of chromatin fibers. In this review, we examine the evolution and the current state of research on the morphological organization of mitotic chromosomes.
1880年，巴拉内茨基首次描述了染色体内纤维。从那时起，人们在有丝分裂染色体内部描述了大量的纤维状亚结构，已发表的数据表明，染色体可能是染色质纤维分层折叠的结果。在这篇综述中，我们考察了有丝分裂染色体形态组织研究的发展历程和现状。
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