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An Overview of Concentrated Insulin Products.

作者信息

Painter Nathan A, Sisson Evan

机构信息

University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Science, La Jolla, CA.

Virginia Commonwealth University School of Pharmacy, Pharmacotherapy and Outcomes Science, Richmond, VA.

出版信息

Diabetes Spectr. 2016 Aug;29(3):136-40. doi: 10.2337/diaspect.29.3.136.

DOI:10.2337/diaspect.29.3.136
PMID:27574366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5001226/
Abstract

IN BRIEF This article provides a summary of the use of available concentrated insulins in the outpatient treatment of patients with diabetes. Concentrated insulins work through the same mechanisms as other insulin products. They vary from each other in concentrations and pharmacokinetic/pharmacodynamics profiles but are each similar to their U-100 concentration counterparts. Patient education is important to minimize errors and the risk of hypoglycemia when using these insulin formulations.

摘要

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本文引用的文献

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Erratum. Classification and diagnosis of diabetes. Sec. 2. In Standards of Medical Care in Diabetes-2016. Diabetes Care 2016;39(Suppl. 1):S13-S22.勘误。糖尿病的分类与诊断。第2节。载于《2016年糖尿病医疗护理标准》。《糖尿病护理》2016年;39(增刊1):S13 - S22。
Diabetes Care. 2016 Sep;39(9):1653. doi: 10.2337/dc16-er09.
2
Bioequivalence and comparative pharmacodynamics of insulin lispro 200 U/mL relative to insulin lispro (Humalog®) 100 U/mL.胰岛素赖脯 200U/mL 与胰岛素赖脯(优泌乐)100U/mL 的生物等效性和比较药效学。
Clin Pharmacol Drug Dev. 2016 Jan;5(1):69-75. doi: 10.1002/cpdd.221. Epub 2015 Oct 5.
3
TWO TREATMENT APPROACHES FOR HUMAN REGULAR U-500 INSULIN IN PATIENTS WITH TYPE 2 DIABETES NOT ACHIEVING ADEQUATE GLYCEMIC CONTROL ON HIGH-DOSE U-100 INSULIN THERAPY WITH OR WITHOUT ORAL AGENTS: A RANDOMIZED, TITRATION-TO-TARGET CLINICAL TRIAL.两种治疗方法用于接受高剂量U-100胰岛素治疗(联合或不联合口服药物)血糖控制仍不佳的2型糖尿病患者的人常规U-500胰岛素治疗:一项随机、滴定至目标的临床试验
Endocr Pract. 2015 Jul;21(7):782-93. doi: 10.4158/EP15612.OR. Epub 2015 Mar 26.
4
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Diabetes Care. 2014 Dec;37(12):3235-43. doi: 10.2337/dc14-0990. Epub 2014 Sep 5.
5
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8
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