Gustavsson L, Alling C
Department of Psychiatry and Neurochemistry, Lund University, Sweden.
Alcohol Alcohol. 1989;24(3):193-6.
The aim of this study was to compare the effects of different ethanol administration procedures on synaptosomal concentrations of acidic phospholipids. The concentrations of phosphatidylinositol and phosphatidylserine were significantly increased after intermittent ethanol exposure for one week but were unaltered after one or three weeks of continuous ethanol administration. The results indicate the importance of drinking pattern for changes in synaptosomal acidic phospholipids.
本研究的目的是比较不同乙醇给药程序对突触体酸性磷脂浓度的影响。间歇性乙醇暴露一周后,磷脂酰肌醇和磷脂酰丝氨酸的浓度显著增加,但连续乙醇给药一周或三周后,其浓度未发生改变。结果表明饮酒模式对突触体酸性磷脂变化的重要性。